Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ADRB3_HUMAN
Description:adrenoceptor beta 3 [Source:HGNC Symbol;Acc:288]
Location:chr8 p11.23
Node attribute:receptor; GPCR

Phosphorylation site
ADRB3_HUMAN do not have phosphorylation site.

Dephosphorylation site
ADRB3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000343782A167VCOSMICLung Cancer20668451
ENSP00000343782P92RCOSMICLung Cancer20668451

Differential expressed protein
ADRB3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ADRB3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DOPO_HUMANADRB3_HUMANligand -> receptorHPMR
ADRB3_HUMANGNAS2_HUMANGPCR -> GproteingpDB
ADRB3_HUMANGNAO_HUMANGPCR -> GproteingpDB
ADRB3_HUMANGNAI1_HUMANGPCR -> GproteingpDB
ADRB3_HUMANGNAS1_HUMANGPCR -> GproteingpDB
ADRB3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ADRB3_HUMANGNAI2_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction
hsa04970Salivary secretion
hsa04020Calcium signaling pathway
hsa04144Endocytosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0040015negative regulation of multicellular organism growIEAbiological_process
GO:0009409response to coldIEAbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupTASbiological_process
GO:0005975carbohydrate metabolic processTASbiological_process
GO:0031649heat generationIEAbiological_process
GO:0031699beta-3 adrenergic receptor bindingIEAmolecular_function
GO:0006091generation of precursor metabolites and energyTASbiological_process
GO:0046677response to antibioticIEAbiological_process
GO:0015052beta3-adrenergic receptor activityIMPmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0051380norepinephrine bindingIDAmolecular_function
GO:0043410positive regulation of MAPK cascadeIDAbiological_process
GO:0006112energy reserve metabolic processTASbiological_process
GO:0007189adenylate cyclase-activating G-protein coupled recIEAbiological_process
GO:0002024diet induced thermogenesisIEAbiological_process
GO:0042803protein homodimerization activityIDAmolecular_function
GO:0004939beta-adrenergic receptor activityIDAmolecular_function
GO:0043235receptor complexIDAcellular_component
GO:0016020membraneIEAcellular_component
GO:0002025vasodilation by norepinephrine-epinephrine involveIEAbiological_process
GO:0007568agingIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0007190activation of adenylate cyclase activityIDAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0042755eating behaviorIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0007188adenylate cyclase-modulating G-protein coupled recTASbiological_process
GO:0051379epinephrine bindingIEAmolecular_function
GO:0050873brown fat cell differentiationIEAbiological_process
GO:0005634nucleusIEAcellular_component


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