Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FSHR_HUMAN
Description:follicle stimulating hormone receptor [Source:HGNC Symbol;Acc:3969]
Location:chr2 p16.3
Node attribute:GPCR; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y250RARSTyNLKKLPhosphoSitePlus
S218VFHGAsGPVILPhosphoSitePlus
S390VILTTsQYKLT7tm_1PhosphoSitePlus
T228LDISRtRIHSLPhosphoSitePlus
S226VILDIsRTRIHPhosphoSitePlus

Dephosphorylation site
FSHR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000306780A473EBIOMARTBreast Cancer21930507, 21930502
ENSP00000306780L174VBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
FSHR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
FSHR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FSHR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
FSHR_HUMANGNAI2_HUMANGPCR -> GproteingpDB
FSHR_HUMANGNAS2_HUMANGPCR -> GproteingpDB
FSHR_HUMANGNAO_HUMANGPCR -> GproteingpDB
FSHR_HUMANGNAS1_HUMANGPCR -> GproteingpDB
FSHR_HUMANGNAI1_HUMANGPCR -> GproteingpDB
GLHA_HUMANFSHR_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005768endosomeIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0042699follicle-stimulating hormone signaling pathwayTASbiological_process
GO:0007292female gamete generationTASbiological_process
GO:0004963follicle-stimulating hormone receptor activityIEAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0008585female gonad developmentTASbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0035093spermatogenesis, exchange of chromosomal proteinsIEAbiological_process
GO:0007283spermatogenesisTASbiological_process
GO:0033044regulation of chromosome organizationIEAbiological_process
GO:0007189adenylate cyclase-activating G-protein coupled recIEAbiological_process
GO:0008584male gonad developmentIEPbiological_process
GO:0008406gonad developmentTASbiological_process
GO:0045056transcytosisIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0009986cell surfaceIEAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0017046peptide hormone bindingIEAmolecular_function


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