| UniProt/SwissProt ID: | RL3R1_HUMAN |
| Description: | relaxin/insulin-like family peptide receptor 3 [Source:HGNC Symbol;Acc:24883] |
| Location: | chr5 p13.2 |
| Node attribute: | receptor; GPCR |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y460 | YSGGRyDLLPS | PhosphoSitePlus | |
| Y469 | PSSSAy_____ | PhosphoSitePlus | |
| Dephosphorylation site |
| RL3R1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000328708 | I352M | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000328708 | A318T | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000328708 | A185V | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| RL3R1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RL3R1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| REL3_HUMAN | RL3R1_HUMAN | ligand -> receptor | HPMR |
| RL3R1_HUMAN | GNAO_HUMAN | GPCR -> Gprotein | gpDB |
| RL3R1_HUMAN | GNAI1_HUMAN | GPCR -> Gprotein | gpDB |
| RL3R1_HUMAN | GNAI3_HUMAN | GPCR -> Gprotein | gpDB |
| RL3R1_HUMAN | GNAI2_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| RL3R1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0051482 | elevation of cytosolic calcium ion concentration i | IEA | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0004982 | N-formyl peptide receptor activity | IEA | molecular_function |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0008528 | G-protein coupled peptide receptor activity | IEA | molecular_function |