| UniProt/SwissProt ID: | TBB8_HUMAN |
| Description: | tubulin, beta 8 class VIII [Source:HGNC Symbol;Acc:20773] |
| Location: | chrHG905_PATCH p15.3 |
| Node attribute: | effector |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y340 | DKNSSyFADWL | Tubulin_C | PhosphoSitePlus |
| Y281 | RGSQQyRALTV | Tubulin_C | PhosphoSitePlus |
| S278 | LTSRGsQQYRA | Tubulin_C | PhosphoSitePlus |
| Y422 | DLVSEyQQYQD | PhosphoSitePlus | |
| Y183 | TVVEPyNATLS | Tubulin | PhosphoSitePlus |
| S339 | QDKNSsYFADW | Tubulin_C | PhosphoSitePlus |
| Y159 | KIREEyPDRII | Tubulin | PhosphoSitePlus |
| S275 | FAPLTsRGSQQ | Tubulin_C | PhosphoSitePlus |
| Y425 | SEYQQyQDATA | PhosphoSitePlus | |
| T274 | GFAPLtSRGSQ | Tubulin_C | PhosphoSitePlus |
| Y59 | ASGGRyVPRAV | Tubulin | PhosphoSitePlus |
| Dephosphorylation site |
| TBB8_HUMAN do not have dephosphorylation site. |
| Mutation site |
| TBB8_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000328808 | Non-small cell lung carcinoma | Treatment (none vs CIGB-300 treatment) | cell line | Up | 2.3 | 20804217 |
| Hyperphosphorylation site |
| TBB8_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GBG12_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GNAQ_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBG10_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBG1_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBG3_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GNAS1_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBG11_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBB3_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBB2_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBB5_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GNAI2_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GNAS2_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBB1_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GNAI1_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBG13_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GNAO_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBG5_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBG8_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GNAI3_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| GBG2_HUMAN | TBB8_HUMAN | Gprotein -> effector | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04540 | Gap junction |
| hsa05130 | Pathogenic Escherichia coli infection |
| hsa04145 | Phagosome |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0015630 | microtubule cytoskeleton | IDA | cellular_component |
| GO:0007018 | microtubule-based movement | IEA | biological_process |
| GO:0006184 | GTP catabolic process | IEA | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0051258 | protein polymerization | IEA | biological_process |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0043234 | protein complex | IEA | cellular_component |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005198 | structural molecule activity | IEA | molecular_function |
| GO:0005874 | microtubule | IEA | cellular_component |