| UniProt/SwissProt ID: | GNAI1_HUMAN |
| Description: | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 [Source:HGNC Symbol;Acc:4384] |
| Location: | chr7 q21.11 |
| Node attribute: | Gprotein |
|
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|
| Y320 | DTKEIyTHFTC | G-alpha | PhosphoSitePlus |
| Y155 | DSAAYyLNDLD | G-alpha | PhosphoSitePlus |
|
GNAI1_HUMAN do not have dephosphorylation site.
|
|
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|
| ENSP00000343027 | E289Q | COSMIC | Head and Neck Cancer | 21798897 |
ENSP00000343027 | D309Y | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000343027 | D193N | COSMIC | Central Nervous System Neoplasms | 18772890 |
|
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|
| ENSP00000343027 | Testicular Cancer | Normal vs. Cancer | cell line | Up | | 18489135 |
|
| GNAI1_HUMAN do not have hyperphosphorylation site. |
|
| GO ID | GO_Term | Evidence | Ontology |
|---|
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0006906 | vesicle fusion | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0051301 | cell division | IMP | biological_process |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0007268 | synaptic transmission | TAS | biological_process |
| GO:0030496 | midbody | IDA | cellular_component |
| GO:0045121 | membrane raft | IEA | cellular_component |
| GO:0019001 | guanyl nucleotide binding | IEA | molecular_function |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0007193 | adenylate cyclase-inhibiting G-protein coupled rec | TAS | biological_process |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0030168 | platelet activation | TAS | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0043434 | response to peptide hormone stimulus | ISS | biological_process |
| GO:0003924 | GTPase activity | IBA | molecular_function |
| GO:0031234 | extrinsic to internal side of plasma membrane | IBA | cellular_component |
| GO:0006184 | GTP catabolic process | IBA | biological_process |
| GO:0004871 | signal transducer activity | IEA | molecular_function |
| GO:0007596 | blood coagulation | TAS | biological_process |
| GO:0005813 | centrosome | IDA | cellular_component |
| GO:0007049 | cell cycle | IEA | biological_process |
| GO:0042588 | zymogen granule | IEA | cellular_component |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0031821 | G-protein coupled serotonin receptor binding | IEA | molecular_function |
| GO:0031683 | G-protein beta/gamma-subunit complex binding | IBA | molecular_function |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0031821 | G-protein coupled serotonin receptor binding | IBA | molecular_function |
| GO:0005834 | heterotrimeric G-protein complex | IBA | cellular_component |
|
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Stack trace:
#0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli))
#1 {main}
thrown in
/usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line
23
