| UniProt/SwissProt ID: | ADA1D_HUMAN |
| Description: | adrenoceptor alpha 1D [Source:HGNC Symbol;Acc:280] |
| Location: | chr20 p13 |
| Node attribute: | GPCR; receptor; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S201 | VGVRHsLKYPA | 7tm_1 | PhosphoSitePlus |
| Dephosphorylation site |
| ADA1D_HUMAN do not have dephosphorylation site. |
| Mutation site |
| ADA1D_HUMAN do not have mutation site. |
| Differential expressed protein |
| ADA1D_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ADA1D_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| DOPO_HUMAN | ADA1D_HUMAN | ligand -> receptor | HPMR |
| ADA1D_HUMAN | GNAQ_HUMAN | GPCR -> Gprotein | gpDB |
| ADA1D_HUMAN | GNA11_HUMAN | GPCR -> Gprotein | gpDB |
| IP3KA_HUMAN | ADA1D_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04020 | Calcium signaling pathway |
| hsa04970 | Salivary secretion |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0007267 | cell-cell signaling | TAS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0007275 | multicellular organismal development | TAS | biological_process |
| GO:0008284 | positive regulation of cell proliferation | TAS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007188 | adenylate cyclase-modulating G-protein coupled rec | TAS | biological_process |
| GO:0008283 | cell proliferation | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0006259 | DNA metabolic process | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0001994 | norepinephrine-epinephrine vasoconstriction involv | IEA | biological_process |
| GO:0004937 | alpha1-adrenergic receptor activity | IEA | molecular_function |
| GO:0001986 | negative regulation of the force of heart contract | IEA | biological_process |