Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GHSR_HUMAN
Description:growth hormone secretagogue receptor [Source:HGNC Symbol;Acc:4267]
Location:chr3 q26.31
Node attribute:GPCR; receptor; PPI(target)

Phosphorylation site
GHSR_HUMAN do not have phosphorylation site.

Dephosphorylation site
GHSR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000241256L210HCOSMICOvarian Cancer21720365
ENSP00000241256V249MCOSMICCentral Nervous System Neoplasms18772396
ENSP00000241256S252LCOSMICLung Cancer20668451

Differential expressed protein
GHSR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GHSR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GHRL_HUMANGHSR_HUMANligand -> receptorHPMR
CORT_HUMANGHSR_HUMANligand -> receptorHPMR
GHSR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
GHSR_HUMANGNA11_HUMANGPCR -> GproteingpDB
IP3KA_HUMANGHSR_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005886plasma membraneTAScellular_component
GO:0045121membrane raftIDAcellular_component
GO:0030252growth hormone secretionIEAbiological_process
GO:0032094response to foodIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0032100positive regulation of appetiteIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIDAbiological_process
GO:0032691negative regulation of interleukin-1 beta productiIDAbiological_process
GO:0008154actin polymerization or depolymerizationIDAbiological_process
GO:0030252growth hormone secretionTASbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0016520growth hormone-releasing hormone receptor activityIDAmolecular_function
GO:0042562hormone bindingIEAmolecular_function
GO:0008343adult feeding behaviorISSbiological_process
GO:0042536negative regulation of tumor necrosis factor biosyIDAbiological_process
GO:0009986cell surfaceIDAcellular_component
GO:0043568positive regulation of insulin-like growth factor IEAbiological_process
GO:0009725response to hormone stimulusIDAbiological_process
GO:0046697decidualizationIDAbiological_process
GO:0032869cellular response to insulin stimulusIEAbiological_process
GO:0051963regulation of synapse assemblyIEAbiological_process
GO:0045923positive regulation of fatty acid metabolic procesIEAbiological_process
GO:0032100positive regulation of appetiteISSbiological_process
GO:0001616growth hormone secretagogue receptor activityIDAmolecular_function
GO:0040018positive regulation of multicellular organism growIMPbiological_process
GO:0050728negative regulation of inflammatory responseIDAbiological_process
GO:0004930G-protein coupled receptor activityIDAmolecular_function
GO:0043005neuron projectionIDAcellular_component
GO:0009755hormone-mediated signaling pathwayIDAbiological_process
GO:0046676negative regulation of insulin secretionIEAbiological_process
GO:0017046peptide hormone bindingIEAmolecular_function
GO:0045409negative regulation of interleukin-6 biosynthetic IDAbiological_process
GO:0008343adult feeding behaviorIEAbiological_process
GO:0043134regulation of hindgut contractionIEAbiological_process


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