| UniProt/SwissProt ID: | P2Y11_HUMAN |
| Description: | purinergic receptor P2Y, G-protein coupled, 11 [Source:HGNC Symbol;Acc:8540] |
| Location: | chr19 p13.2 |
| Node attribute: | GPCR |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S235 | RAVLRsPGMTV | 7tm_1 | PhosphoSitePlus |
| T110 | ERFLFtCNLLG | 7tm_1 | PhosphoSitePlus |
| Dephosphorylation site |
| P2Y11_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000323872 | Q304P | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| P2Y11_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| P2Y11_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| P2Y11_HUMAN | GNAS1_HUMAN | GPCR -> Gprotein | gpDB |
| P2Y11_HUMAN | GNAQ_HUMAN | GPCR -> Gprotein | gpDB |
| P2Y11_HUMAN | GNA11_HUMAN | GPCR -> Gprotein | gpDB |
| P2Y11_HUMAN | GNAS2_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0005887 | integral to plasma membrane | IC | cellular_component |
| GO:0030594 | neurotransmitter receptor activity | IDA | molecular_function |
| GO:0007190 | activation of adenylate cyclase activity | TAS | biological_process |
| GO:0023041 | neuronal signal transduction | IDA | biological_process |
| GO:0006952 | defense response | TAS | biological_process |
| GO:0004872 | receptor activity | TAS | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007200 | phospholipase C-activating G-protein coupled recep | TAS | biological_process |
| GO:0045031 | ATP-activated nucleotide receptor activity | IDA | molecular_function |
| GO:0007268 | synaptic transmission | IDA | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IDA | biological_process |
| GO:0019722 | calcium-mediated signaling | IDA | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0045028 | G-protein coupled purinergic nucleotide receptor a | IEA | molecular_function |
| GO:0071318 | cellular response to ATP | IDA | biological_process |