Phosphorylation

Protein information

UniProt/SwissProt ID:	TA2R_HUMAN
Description:	thromboxane A2 receptor [Source:HGNC Symbol;Acc:11608]
Location:	chr19 p13.3
Node attribute:	substrate; GPCR; PPI(target)

Position	PhosphoPeptide	Source
S329	STRPRsLSLQP	HPRD
S331	RPRSLsLQPQL	HPRD

TA2R_HUMAN do not have dephosphorylation site.

TA2R_HUMAN do not have mutation site.

TA2R_HUMAN is not differential expressed protein.

TA2R_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
TA2R_HUMAN	GNAQ_HUMAN	GPCR -> Gprotein	gpDB
TA2R_HUMAN	GNA13_HUMAN	GPCR -> Gprotein	gpDB
TA2R_HUMAN	GNA12_HUMAN	GPCR -> Gprotein	gpDB
TA2R_HUMAN	GNA11_HUMAN	GPCR -> Gprotein	gpDB
KPCA_HUMAN	TA2R_HUMAN	kinase -> substrate	Robert H Newman (2013)
GLHA_HUMAN	TA2R_HUMAN	other	KEGG

KEGG Pathway

KEGG ID	Pathway
hsa04080	Neuroactive ligand-receptor interaction
hsa04020	Calcium signaling pathway

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0005886	plasma membrane	TAS	cellular_component
GO:0045777	positive regulation of blood pressure	IEA	biological_process
GO:0032496	response to lipopolysaccharide	IEA	biological_process
GO:0007596	blood coagulation	TAS	biological_process
GO:0006954	inflammatory response	IEA	biological_process
GO:0007186	G-protein coupled receptor signaling pathway	TAS	biological_process
GO:0030168	platelet activation	TAS	biological_process
GO:0019229	regulation of vasoconstriction	IEA	biological_process
GO:0005887	integral to plasma membrane	TAS	cellular_component
GO:0045987	positive regulation of smooth muscle contraction	IEA	biological_process
GO:0004930	G-protein coupled receptor activity	IEA	molecular_function
GO:0042493	response to drug	IEA	biological_process
GO:0005085	guanyl-nucleotide exchange factor activity	TAS	molecular_function
GO:0045766	positive regulation of angiogenesis	IEA	biological_process
GO:0004961	thromboxane A2 receptor activity	TAS	molecular_function
GO:0019932	second-messenger-mediated signaling	IEA	biological_process
GO:0016021	integral to membrane	IEA	cellular_component
GO:0045907	positive regulation of vasoconstriction	IEA	biological_process
GO:0004960	thromboxane receptor activity	IEA	molecular_function
GO:0007584	response to nutrient	IEA	biological_process
GO:0005515	protein binding	IPI	molecular_function
GO:0007204	elevation of cytosolic calcium ion concentration	IEA	biological_process
GO:0001669	acrosomal vesicle	IEA	cellular_component

Human Phosphorylation Mediated
Signaling Transduction Network