Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:V1BR_HUMAN
Description:arginine vasopressin receptor 1B [Source:HGNC Symbol;Acc:896]
Location:chrHG1293_PATCH q32.
Node attribute:receptor; GPCR

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S371RLSDGsLSSRHPhosphoSitePlus
Y338CNPWIyMGFNSHPRD
S267LPSRVsSINTI7tm_1PhosphoSitePlus
T258STLAAtTRGLP7tm_1PhosphoSitePlus
T271VSSINtISRAK7tm_1PhosphoSitePlus

Dephosphorylation site
V1BR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000356094A188ETCGAOvarian Cancer21720365, 18772890
ENSP00000356094A188ECOSMICOvarian Cancer21720365
ENSP00000356094I163NCOSMICOvarian Cancer21720365
ENSP00000356094T129MCOSMICIntestines Cancer17932254
ENSP00000356094S299fs*82COSMICOvarian Cancer21720365

Differential expressed protein
V1BR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
V1BR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NEU2_HUMANV1BR_HUMANligand -> receptorHPMR
V1BR_HUMANGNA11_HUMANGPCR -> GproteingpDB
V1BR_HUMANGNAQ_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04020Calcium signaling pathway
hsa04270Vascular smooth muscle contraction
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005768endosomeTAScellular_component
GO:0005000vasopressin receptor activityIEAmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0005080protein kinase C bindingTASmolecular_function
GO:0007204elevation of cytosolic calcium ion concentrationTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0007202activation of phospholipase C activityTASbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0001992regulation of systemic arterial blood pressure by IEAbiological_process
GO:0005886plasma membraneTAScellular_component


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