Phosphorylation

You are querying signaling transduction network mediated by ADA1D_HUMAN in Intestines Cancer.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	DOPO_HUMAN	ADA1D_HUMAN	ligand -> receptor	HPMR
2	ADA1D_HUMAN	GNAQ_HUMAN	GPCR -> Gprotein	gpDB
3	ADA1D_HUMAN	GNA11_HUMAN	GPCR -> Gprotein	gpDB
4	GNAQ_HUMAN	BTK_HUMAN	Gprotein -> effector	gpDB
5	GNAQ_HUMAN	KPCD1_HUMAN	Gprotein -> effector	gpDB
6	GNAQ_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
7	GNAQ_HUMAN	PK3CA_HUMAN	Gprotein -> effector	gpDB
8	GNA11_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
9	BTK_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
10	KPCD1_HUMAN	KSYK_HUMAN	kinase -> substrate	NetPath
11	BTK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
12	ARBK1_HUMAN	P53_HUMAN	kinase -> substrate	Robert H Newman (2013)
13	BTK_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
14	BTK_HUMAN	STA5B_HUMAN	kinase -> substrate	Robert H Newman (2013)
15	BTK_HUMAN	MK01_HUMAN	kinase -> substrate	Robert H Newman (2013)
16	PK3CA_HUMAN	KS6B1_HUMAN	kinase -> substrate	HPRD
17	BTK_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
18	BTK_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
19	BTK_HUMAN	SMAD3_HUMAN	kinase -> substrate	Robert H Newman (2013)
20	BTK_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
21	BTK_HUMAN	STA5A_HUMAN	kinase -> substrate	HPRD; RegPhos
22	BTK_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
23	BTK_HUMAN	CDK9_HUMAN	kinase -> substrate	Robert H Newman (2013)
24	BTK_HUMAN	ITK_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
25	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
26	KSYK_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
27	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
28	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
29	KS6A2_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
30	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
31	KSYK_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
32	MK01_HUMAN	SP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
33	KS6B1_HUMAN	HSF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
34	MK01_HUMAN	MYC_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
35	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
36	MK01_HUMAN	PPARA_HUMAN	kinase -> substrate	HPRD
37	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
38	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
39	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
40	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
41	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
42	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
43	SMAD3_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
44	MK01_HUMAN	STK16_HUMAN	kinase -> substrate	Robert H Newman (2013)
45	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
46	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
47	KS6A2_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
48	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
49	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
50	P53_HUMAN	ATF3_HUMAN	TF -> target gene	TRANSFAC
51	KS6A2_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
52	KS6A2_HUMAN	KS6A1_HUMAN	kinase -> substrate	RegPhos
53	MK01_HUMAN	TFE2_HUMAN	kinase -> substrate	HPRD; NetPath
54	P53_HUMAN	P73_HUMAN	TF -> target gene	KEGG; TRANSFAC
55	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
56	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
57	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
58	MK01_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD
59	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
60	MK01_HUMAN	GSK3B_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	KS6A2_HUMAN	SRF_HUMAN	kinase -> substrate	RegPhos
62	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
63	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
64	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
65	MK01_HUMAN	CEBPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
66	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
67	MK01_HUMAN	STF1_HUMAN	kinase -> substrate	HPRD
68	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
69	MK01_HUMAN	SRBP2_HUMAN	kinase -> substrate	Robert H Newman (2013)
70	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
71	KS6A2_HUMAN	FOS_HUMAN	kinase -> substrate	RegPhos
72	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
73	KS6A2_HUMAN	NR4A1_HUMAN	kinase -> substrate	RegPhos
74	MK01_HUMAN	ELK1_HUMAN	kinase -> substrate	NetPath
75	MK01_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
76	MK01_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD
77	MK01_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD
78	MK01_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
79	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
80	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
81	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
82	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
83	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
84	MK01_HUMAN	CEBPB_HUMAN	kinase -> substrate	HPRD
85	STA5A_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
86	KS6B1_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
87	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
88	MK01_HUMAN	MP2K1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
89	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
90	KS6B1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
91	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
92	MK01_HUMAN	RXRA_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
93	MK01_HUMAN	SRBP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
94	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
95	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
96	MK01_HUMAN	ELK4_HUMAN	kinase -> substrate	KEGG
97	MK01_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
98	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
99	KS6B1_HUMAN	MTOR_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
100	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
101	MK01_HUMAN	PKN1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
102	MK01_HUMAN	MITF_HUMAN	kinase -> substrate	NetPath
103	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
104	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
105	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
106	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
107	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
108	MK01_HUMAN	THB_HUMAN	kinase -> substrate	Robert H Newman (2013)
109	MK01_HUMAN	JUN_HUMAN	kinase -> substrate	KEGG
110	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
111	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
112	MK01_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
113	MK01_HUMAN	PRGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
114	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
115	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
116	KS6B1_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
117	MK01_HUMAN	BCL6_HUMAN	kinase -> substrate	NetPath
118	KS6A2_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
119	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
120	KS6A2_HUMAN	CEBPB_HUMAN	kinase -> substrate	RegPhos
121	MK01_HUMAN	SMAD4_HUMAN	kinase -> substrate	HPRD
122	CDK9_HUMAN	CHK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
123	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	MK01_HUMAN	SOS1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
125	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
126	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
127	MK01_HUMAN	MYB_HUMAN	kinase -> substrate	HPRD
128	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
129	ITK_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
130	MK01_HUMAN	FOS_HUMAN	kinase -> substrate; other	KEGG
131	KSYK_HUMAN	KS6A1_HUMAN	kinase -> substrate	NetPath
132	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
133	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
134	SP1_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
135	SP1_HUMAN	AP2C_HUMAN	TF -> target gene	TRANSFAC
136	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
137	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
138	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
139	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
140	STK16_HUMAN	IRF5_HUMAN	kinase -> substrate	Robert H Newman (2013)
141	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
142	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
143	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
144	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
145	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
146	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
147	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
148	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
149	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
150	SP1_HUMAN	SP3_HUMAN	TF -> target gene	TRANSFAC
151	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
152	SP1_HUMAN	CDK2_HUMAN	TF -> target gene	TRANSFAC
153	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
154	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
155	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
156	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
157	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
158	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
159	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
160	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
161	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
162	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
163	SP1_HUMAN	TGFR2_HUMAN	TF -> target gene	TRANSFAC
164	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
165	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
166	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
167	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
168	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
169	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
170	SP1_HUMAN	RARA_HUMAN	TF -> target gene	TRANSFAC
171	SP1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
172	SP1_HUMAN	HNF4A_HUMAN	TF -> target gene	TRANSFAC
173	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
174	SP1_HUMAN	PHX2A_HUMAN	TF -> target gene	TRANSFAC
175	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
176	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
177	SP1_HUMAN	MAZ_HUMAN	TF -> target gene	TRANSFAC
178	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
179	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
180	CHK2_HUMAN	E2F1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
181	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
182	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
183	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
184	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
185	CDK2_HUMAN	TFDP1_HUMAN	kinase -> substrate	RegPhos
186	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
187	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
188	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
189	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
190	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
191	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
192	TGFR2_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
193	CDK2_HUMAN	NFYA_HUMAN	kinase -> substrate	HPRD
194	IP3KA_HUMAN	ADA1D_HUMAN	other	KEGG

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network