Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IP3KA_HUMAN
Description:inositol-trisphosphate 3-kinase A [Source:HGNC Symbol;Acc:6178]
Location:chr15 q15.1
Node attribute:Enzyme(target); substrate; PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T311AQRAVtKPRYMPKCaRegPhos
T311AQRAVtKPRYMPRKACAHPRD
T311AQRAVtKPRYMPKACaRegPhos
T311AQRAVtKPRYMCaM-KII_alphaphosphoELM
T311AQRAVtKPRYMCaMK2aRegPhos
T311AQRAVtKPRYMIPKPhosphoSitePlus
S197AGHTGsFKAAGPhosphoSitePlus
S20GARPCsPGLERPhosphoSitePlus
S323WREGIsSSTTLIPKPhosphoSitePlus
T311AQRAVtKPRYMPKC_groupphosphoELM; RegPhos
T311AQRAVtKPRYMPRKCAHPRD

Dephosphorylation site
IP3KA_HUMAN do not have dephosphorylation site.

Mutation site
IP3KA_HUMAN do not have mutation site.

Differential expressed protein
IP3KA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IP3KA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANIP3KA_HUMANkinase -> substrateHPRD
PLCD3_HUMANIP3KA_HUMANenzyme catalysisKEGG
ITPR1_HUMANIP3KA_HUMANenzyme catalysisKEGG
PI5PA_HUMANIP3KA_HUMANenzyme catalysisKEGG
IP3KA_HUMANACTHR_HUMANotherKEGG
IP3KA_HUMANGHSR_HUMANotherKEGG
IP3KA_HUMANTAAR9_HUMANotherKEGG
IP3KA_HUMANGPR83_HUMANotherKEGG
IP3KA_HUMANOX1R_HUMANotherKEGG
IP3KA_HUMANFPR1_HUMANotherKEGG
IP3KA_HUMANNTR2_HUMANotherKEGG
IP3KA_HUMANNPFF2_HUMANotherKEGG
IP3KA_HUMAN5HT1A_HUMANotherKEGG
IP3KA_HUMANUR2R_HUMANotherKEGG
IP3KA_HUMANC3AR_HUMANotherKEGG
IP3KA_HUMANSSR1_HUMANotherKEGG
IP3KA_HUMANAPJ_HUMANotherKEGG
IP3KA_HUMANOPRD_HUMANotherKEGG
IP3KA_HUMANMTLR_HUMANotherKEGG
IP3KA_HUMANDRD1_HUMANotherKEGG
IP3KA_HUMANHRH3_HUMANotherKEGG
IP3KA_HUMANCALL6_HUMANotherKEGG
IP3KA_HUMANAGTR1_HUMANotherKEGG
IP3KA_HUMANNMUR1_HUMANotherKEGG
IP3KA_HUMANV1AR_HUMANotherKEGG
IP3KA_HUMANMSHR_HUMANotherKEGG
IP3KA_HUMANCCKAR_HUMANotherKEGG
IP3KA_HUMANKISSR_HUMANotherKEGG
IP3KA_HUMANEDNRA_HUMANotherKEGG
IP3KA_HUMANOXYR_HUMANotherKEGG
IP3KA_HUMANACM1_HUMANotherKEGG
IP3KA_HUMANNK2R_HUMANotherKEGG
IP3KA_HUMANC5AR_HUMANotherKEGG
IP3KA_HUMANNK3R_HUMANotherKEGG
IP3KA_HUMANGALR1_HUMANotherKEGG
IP3KA_HUMANBKRB1_HUMANotherKEGG
IP3KA_HUMANNPBW1_HUMANotherKEGG
IP3KA_HUMANADA1D_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04070Phosphatidylinositol signaling system
hsa01100Metabolic pathways
hsa04020Calcium signaling pathway
hsa00562Inositol phosphate metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005516calmodulin bindingIEAmolecular_function
GO:0006020inositol metabolic processIEAbiological_process
GO:0008440inositol-1,4,5-trisphosphate 3-kinase activityIEAmolecular_function
GO:0004683calmodulin-dependent protein kinase activityIEAmolecular_function
GO:0007165signal transductionTASbiological_process
GO:0005524ATP bindingIEAmolecular_function


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