Phosphorylation

You are querying signaling transduction network mediated by 5HT2A_HUMAN in Intestines Cancer.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	TPH1_HUMAN	5HT2A_HUMAN	ligand -> receptor	HPMR
2	5HT2A_HUMAN	GNAQ_HUMAN	GPCR -> Gprotein	gpDB
3	5HT2A_HUMAN	GNA11_HUMAN	GPCR -> Gprotein	gpDB
4	GNAQ_HUMAN	KPCD1_HUMAN	Gprotein -> effector	gpDB
5	GNAQ_HUMAN	BTK_HUMAN	Gprotein -> effector	gpDB
6	GNAQ_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
7	GNAQ_HUMAN	PK3CA_HUMAN	Gprotein -> effector	gpDB
8	GNA11_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
9	KPCD1_HUMAN	KSYK_HUMAN	kinase -> substrate	NetPath
10	BTK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
11	BTK_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
12	BTK_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
13	ARBK1_HUMAN	P53_HUMAN	kinase -> substrate	Robert H Newman (2013)
14	BTK_HUMAN	MK01_HUMAN	kinase -> substrate	Robert H Newman (2013)
15	BTK_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
16	PK3CA_HUMAN	KS6B1_HUMAN	kinase -> substrate	HPRD
17	BTK_HUMAN	SMAD3_HUMAN	kinase -> substrate	Robert H Newman (2013)
18	BTK_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
19	BTK_HUMAN	CDK9_HUMAN	kinase -> substrate	Robert H Newman (2013)
20	BTK_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
21	BTK_HUMAN	STA5A_HUMAN	kinase -> substrate	HPRD; RegPhos
22	BTK_HUMAN	ITK_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
23	BTK_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
24	BTK_HUMAN	STA5B_HUMAN	kinase -> substrate	Robert H Newman (2013)
25	KSYK_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
26	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
27	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
28	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
29	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
30	MK01_HUMAN	PKN1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
31	P53_HUMAN	P73_HUMAN	TF -> target gene	KEGG; TRANSFAC
32	MK01_HUMAN	PRGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
33	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
34	MK01_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD
35	KS6B1_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
36	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
37	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
38	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
39	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
40	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
41	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
42	MK01_HUMAN	CEBPB_HUMAN	kinase -> substrate	HPRD
43	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
44	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
45	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
46	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
47	MK01_HUMAN	RXRA_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
48	KS6B1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
49	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
50	KS6A2_HUMAN	SRF_HUMAN	kinase -> substrate	RegPhos
51	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
52	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
53	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
54	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
55	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
56	MK01_HUMAN	SP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
57	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
58	MK01_HUMAN	FOS_HUMAN	kinase -> substrate; other	KEGG
59	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
60	MK01_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
62	KS6A2_HUMAN	KS6A1_HUMAN	kinase -> substrate	RegPhos
63	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
64	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
65	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
66	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
67	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
68	KS6A2_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
69	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
70	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
71	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
72	MK01_HUMAN	ELK4_HUMAN	kinase -> substrate	KEGG
73	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
74	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
75	MK01_HUMAN	CEBPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
76	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
77	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
78	CDK9_HUMAN	CHK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
79	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
80	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
81	MK01_HUMAN	MP2K1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
82	KS6B1_HUMAN	HSF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
83	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
84	KS6A2_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
85	KS6B1_HUMAN	MTOR_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
86	KS6B1_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
87	KS6A2_HUMAN	FOS_HUMAN	kinase -> substrate	RegPhos
88	P53_HUMAN	ATF3_HUMAN	TF -> target gene	TRANSFAC
89	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
90	MK01_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD
91	MK01_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
92	MK01_HUMAN	MYC_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
93	MK01_HUMAN	STK16_HUMAN	kinase -> substrate	Robert H Newman (2013)
94	STA5A_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
95	ITK_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
96	MK01_HUMAN	STF1_HUMAN	kinase -> substrate	HPRD
97	MK01_HUMAN	ELK1_HUMAN	kinase -> substrate	NetPath
98	KS6A2_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
99	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
100	MK01_HUMAN	BCL6_HUMAN	kinase -> substrate	NetPath
101	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
102	MK01_HUMAN	SRBP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
103	MK01_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD
104	MK01_HUMAN	TFE2_HUMAN	kinase -> substrate	HPRD; NetPath
105	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
106	KS6A2_HUMAN	NR4A1_HUMAN	kinase -> substrate	RegPhos
107	KSYK_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
108	KS6A2_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
109	MK01_HUMAN	JUN_HUMAN	kinase -> substrate	KEGG
110	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
111	MK01_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
112	MK01_HUMAN	SOS1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
113	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
114	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
115	SMAD3_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
116	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
117	MK01_HUMAN	PPARA_HUMAN	kinase -> substrate	HPRD
118	MK01_HUMAN	MITF_HUMAN	kinase -> substrate	NetPath
119	MK01_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
120	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
121	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
122	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
123	MK01_HUMAN	THB_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	MK01_HUMAN	SRBP2_HUMAN	kinase -> substrate	Robert H Newman (2013)
125	KSYK_HUMAN	KS6A1_HUMAN	kinase -> substrate	NetPath
126	MK01_HUMAN	MYB_HUMAN	kinase -> substrate	HPRD
127	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
128	KS6A2_HUMAN	CEBPB_HUMAN	kinase -> substrate	RegPhos
129	MK01_HUMAN	GSK3B_HUMAN	kinase -> substrate	Robert H Newman (2013)
130	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
131	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
132	MK01_HUMAN	SMAD4_HUMAN	kinase -> substrate	HPRD
133	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
134	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
135	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
136	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
137	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
138	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
139	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
140	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
141	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
142	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
143	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
144	SP1_HUMAN	CDK2_HUMAN	TF -> target gene	TRANSFAC
145	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
146	SP1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
147	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
148	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
149	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
150	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
151	SP1_HUMAN	SP3_HUMAN	TF -> target gene	TRANSFAC
152	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
153	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
154	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
155	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
156	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
157	CHK2_HUMAN	E2F1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
158	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
159	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
160	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
161	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
162	SP1_HUMAN	HNF4A_HUMAN	TF -> target gene	TRANSFAC
163	SP1_HUMAN	AP2C_HUMAN	TF -> target gene	TRANSFAC
164	STK16_HUMAN	IRF5_HUMAN	kinase -> substrate	Robert H Newman (2013)
165	SP1_HUMAN	PHX2A_HUMAN	TF -> target gene	TRANSFAC
166	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
167	SP1_HUMAN	MAZ_HUMAN	TF -> target gene	TRANSFAC
168	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
169	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
170	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
171	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
172	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
173	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
174	SP1_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
175	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
176	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
177	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
178	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
179	SP1_HUMAN	TGFR2_HUMAN	TF -> target gene	TRANSFAC
180	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
181	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
182	SP1_HUMAN	RARA_HUMAN	TF -> target gene	TRANSFAC
183	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
184	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
185	CDK2_HUMAN	NFYA_HUMAN	kinase -> substrate	HPRD
186	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
187	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
188	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
189	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
190	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
191	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
192	TGFR2_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
193	CDK2_HUMAN	TFDP1_HUMAN	kinase -> substrate	RegPhos

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network