| UniProt/SwissProt ID: | P53_HUMAN |
| Description: | tumor protein p53 [Source:HGNC Symbol;Acc:11998] |
| Location: | chr17 p13.1 |
| Node attribute: | gene; PPI(target); PPI(source); substrate; TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S15 | VEPPLsQETFS | P53_TAD | PhosphoSitePlus |
| S215 | NTFRHsVVVPY | Aurora A | phosphoELM |
| S315 | NNTSSsPQPKK | CDK5 | HPRD; RegPhos |
| T18 | PLSQEtFSDLW | CK2a1-rs | RegPhos |
| S6 | MEEPQsDPSVE | CK1a | RegPhos |
| T18 | PLSQEtFSDLW | CSNK2A1 | HPRD |
| S314 | PNNTSsSPQPK | PhosphoSitePlus; HPRD | |
| S33 | ENNVLsPLPSQ | PhosphoSitePlus; HPRD | |
| T55 | IEQWFtEDPGP | Erk2 | RegPhos |
| S183 | HHERCsDSDGL | P53 | PhosphoSitePlus |
| S20 | SQETFsDLWKL | phosphoELM | |
| T81 | APAAPtPAAPA | JNK1 | RegPhos |
| S33 | ENNVLsPLPSQ | ATM | HPRD; RegPhos |
| T284 | GRDRRtEEENL | P53 | PhosphoSitePlus |
| S378 | KGQSTsRHKKL | PRKCA | HPRD |
| S20 | SQETFsDLWKL | CHK1 | phosphoELM; RegPhos |
| S366 | GSRAHsSHLKS | PhosphoSitePlus; HPRD; RegPhos | |
| S46 | DDLMLsPDDIE | DYRK2 | phosphoELM |
| S46 | DDLMLsPDDIE | HIPK2 | HPRD; phosphoELM; RegPhos |
| S6 | MEEPQsDPSVE | P53_TAD | PhosphoSitePlus |
| T150 | LWVDStPPPGT | P53 | PhosphoSitePlus |
| S315 | NNTSSsPQPKK | Aurora A | phosphoELM |
| T211 | LDDRNtFRHSV | P53 | PhosphoSitePlus |
| S15 | VEPPLsQETFS | HPRD; RegPhos | |
| Y327 | PLDGEyFTLQI | P53_tetramer | PhosphoSitePlus |
| S37 | LSPLPsQAMDD | DNA-PK | phosphoELM |
| S9 | PQSDPsVEPPL | CK1a | RegPhos |
| S20 | SQETFsDLWKL | P53_TAD | PhosphoSitePlus |
| S392 | TEGPD | CDK9 | HPRD |
| S392 | TEGPD | CDK2 | HPRD |
| S392 | TEGPD | CDK7 | phosphoELM |
| S15 | VEPPLsQETFS | MAPK1 | HPRD |
| T81 | APAAPtPAAPA | HPRD | |
| S392 | TEGPDsD | p38a | RegPhos |
| S9 | PQSDPsVEPPL | phosphoELM; RegPhos | |
| S15 | VEPPLsQETFS | PRPK | RegPhos |
| S392 | TEGPD | MAPK14 | HPRD |
| S362 | KEPGGsRAHSS | PhosphoSitePlus | |
| T18 | PLSQEtFSDLW | ATR | HPRD; RegPhos |
| S15 | VEPPLsQETFS | ATR | HPRD; RegPhos |
| S37 | LSPLPsQAMDD | CHK1 | RegPhos |
| T18 | PLSQEtFSDLW | TTK | phosphoELM |
| T81 | APAAPtPAAPA | DEC-1_N | PhosphoSitePlus |
| S46 | DDLMLsPDDIE | ATM | HPRD; phosphoELM; RegPhos |
| S15 | VEPPLsQETFS | DNAPK | RegPhos |
| T18 | PLSQEtFSDLW | CSNK1D | HPRD |
| S315 | NNTSSsPQPKK | CDK_group | RegPhos |
| S15 | VEPPLsQETFS | DNA-PK | phosphoELM |
| T377 | KKGQStSRHKK | PhosphoSitePlus | |
| T18 | PLSQEtFSDLW | P53_TAD | PhosphoSitePlus |
| S15 | VEPPLsQETFS | Erk2 | RegPhos |
| S37 | LSPLPsQAMDD | ATM | HPRD; RegPhos |
| S37 | LSPLPsQAMDD | ATR | HPRD; RegPhos |
| S315 | NNTSSsPQPKK | CDC2 | RegPhos |
| S37 | LSPLPsQAMDD | DNAPK | RegPhos |
| S20 | SQETFsDLWKL | CHEK1 | HPRD |
| T18 | PLSQEtFSDLW | CK1d | RegPhos |
| T18 | PLSQEtFSDLW | CK2a1 | RegPhos |
| S99 | SSSVPsQKTYQ | HPRD; phosphoELM; RegPhos | |
| S215 | NTFRHsVVVPY | AurA | RegPhos |
| T18 | PLSQEtFSDLW | CSNK2B | HPRD |
| S315 | NNTSSsPQPKK | AurA | RegPhos |
| S33 | ENNVLsPLPSQ | DNAPK | RegPhos |
| S15 | VEPPLsQETFS | PRKDC | HPRD |
| T18 | PLSQEtFSDLW | VRK1 | HPRD; phosphoELM; RegPhos |
| S378 | KGQSTsRHKKL | CDK7 | phosphoELM; RegPhos |
| S313 | LPNNTsSSPQP | PhosphoSitePlus; HPRD | |
| T55 | IEQWFtEDPGP | MAPK1 | HPRD |
| S106 | KTYQGsYGFRL | PhosphoSitePlus | |
| S15 | VEPPLsQETFS | CHK1 | RegPhos |
| S33 | ENNVLsPLPSQ | PRKDC | HPRD |
| T155 | TPPPGtRVRAM | CSNK2A1 | HPRD |
| S20 | SQETFsDLWKL | DAPK1 | phosphoELM |
| S392 | TEGPDsD | PKR(EIF2AK2 | RegPhos |
| T18 | PLSQEtFSDLW | CK1_group | phosphoELM; RegPhos |
| S269 | LLGRNsFEVRV | P53 | PhosphoSitePlus |
| S99 | SSSVPsQKTYQ | DEC-1_N; P53 | PhosphoSitePlus |
| S46 | DDLMLsPDDIE | PhosphoSitePlus; phosphoELM | |
| S378 | KGQSTsRHKKL | PhosphoSitePlus | |
| S9 | PQSDPsVEPPL | P53_TAD | PhosphoSitePlus |
| T18 | PLSQEtFSDLW | PRKDC | HPRD |
| S371 | SSHLKsKKGQS | PRKCA | HPRD |
| T155 | TPPPGtRVRAM | CK2a1 | RegPhos |
| S20 | SQETFsDLWKL | ATM | HPRD; RegPhos |
| S9 | PQSDPsVEPPL | CSNK1A1 | HPRD |
| S33 | ENNVLsPLPSQ | GSK_group | RegPhos |
| S315 | NNTSSsPQPKK | CDK9 | HPRD; RegPhos |
| S315 | NNTSSsPQPKK | CDK2 | HPRD; RegPhos |
| S15 | VEPPLsQETFS | CHEK1 | HPRD |
| T81 | APAAPtPAAPA | MAPK8 | HPRD |
| S33 | ENNVLsPLPSQ | GSK3B | HPRD; RegPhos |
| S20 | SQETFsDLWKL | CHK2 | phosphoELM; RegPhos |
| S20 | SQETFsDLWKL | PRKDC | HPRD |
| S371 | SSHLKsKKGQS | CDK7 | phosphoELM; RegPhos |
| S33 | ENNVLsPLPSQ | CDK_group | phosphoELM; RegPhos |
| S392 | TEGPD | CSNK2A1 | HPRD |
| S37 | LSPLPsQAMDD | MAPKAPK5 | HPRD; phosphoELM |
| S149 | QLWVDsTPPPG | P53 | PhosphoSitePlus |
| S9 | PQSDPsVEPPL | ATM | HPRD; RegPhos |
| T312 | ALPNNtSSSPQ | PhosphoSitePlus | |
| S20 | SQETFsDLWKL | PLK3 | HPRD; RegPhos |
| S392 | TEGPDsD____ | PhosphoSitePlus | |
| T18 | PLSQEtFSDLW | DNAPK | RegPhos |
| T55 | IEQWFtEDPGP | DEC-1_N | PhosphoSitePlus |
| S20 | SQETFsDLWKL | DNAPK | RegPhos |
| T155 | TPPPGtRVRAM | CK2a1-rs | RegPhos |
| S15 | VEPPLsQETFS | RSK2 | RegPhos |
| S376 | SKKGQsTSRHK | PhosphoSitePlus | |
| T155 | TPPPGtRVRAM | P53 | PhosphoSitePlus |
| S37 | LSPLPsQAMDD | CHEK1 | HPRD |
| S33 | ENNVLsPLPSQ | GSK-3_group | phosphoELM |
| S33 | ENNVLsPLPSQ | CDK5 | HPRD; RegPhos |
| S33 | ENNVLsPLPSQ | CDK7 | phosphoELM; RegPhos |
| S33 | ENNVLsPLPSQ | CDK9 | HPRD; RegPhos |
| S37 | LSPLPsQAMDD | PRKDC | HPRD |
| S392 | TEGPDsD | PKR | RegPhos |
| S371 | SSHLKsKKGQS | PhosphoSitePlus | |
| T18 | PLSQEtFSDLW | P67870(Casein kinase II ) | RegPhos |
| T55 | IEQWFtEDPGP | MAPK_group | phosphoELM; RegPhos |
| S392 | TEGPDsD | CK2a1-rs | RegPhos |
| S371 | SSHLKsKKGQS | PKCa | RegPhos |
| S15 | VEPPLsQETFS | ATM | HPRD; phosphoELM; RegPhos |
| S376 | SKKGQsTSRHK | CDK7 | phosphoELM; RegPhos |
| S392 | TEGPD | phosphoELM | |
| S20 | SQETFsDLWKL | ATR | HPRD; RegPhos |
| S37 | LSPLPsQAMDD | PhosphoSitePlus | |
| S6 | PSVE | CSNK1A1 | HPRD |
| T55 | IEQWFtEDPGP | TAF1 | RegPhos |
| S392 | TEGPD | EIF2AK2 | HPRD |
| S215 | NTFRHsVVVPY | P53 | PhosphoSitePlus |
| S392 | TEGPDsD | CK2a1 | RegPhos |
| S378 | KGQSTsRHKKL | PKCa | RegPhos |
| S315 | NNTSSsPQPKK | PhosphoSitePlus; HPRD; phosphoELM | |
| T387 | KLMFKtEGPDS | PhosphoSitePlus | |
| S392 | TEGPDsD | CK2_group | RegPhos |
| S392 | TEGPDsD | CDK7 | RegPhos |
| S392 | TEGPDsD | CDK2 | RegPhos |
| S392 | TEGPDsD | CDK9 | RegPhos |
| Dephosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S15 | PSVEPPLsQETFSDL | CDC25C | HPRD |
| S315 | LPNNTSSsPQPKKKP | CDC14A | HPRD |
| S315 | LPNNTSSsPQPKKKP | CDC14B | HPRD |
| T55 | DDIEQWFtEDPGPDE | HPRD | |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000269305 | M237I | Ding2008, COSMIC | Head and Neck Cancer | 18428421, 18948947, 21798893 | ENSP00000391127 | C275Y | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | D42Y | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | P190T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | S241F | Sjoblom2006 | Lung Cancer | 1565143, 16959974, 18428421 | ENSP00000391478 | D281R | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | S303T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | A74T | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | R158Y | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | G108S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | P190fs*57 | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000398846 | Q192* | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | L145V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | H214R | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000269305 | F134L | Sjoblom2006 | Intestines Cancer | 16959974, 1905840, 8829653 | ENSP00000269305 | R273L | Ding2008, Sjoblom2006 | Breast Cancer | 16959974, 18428421, 18948947 | ENSP00000269305 | H179R | Ding2008 | Other Cancer(sporadic cancer) | 18428421, 18948947, 1905840, 8829653 | ENSP00000269305 | S240T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | D7H | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | S185T | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | V173L | COSMIC | Ovarian Cancer | 21720365 | ENSP00000269305 | E298* | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000391478 | A276V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | L330P | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | G325E | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | E68Q | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R213* | Ding2008 | Uterine Cancer | 18428421, 18948947 | ENSP00000269305 | K320N | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | R181S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | K24N | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R158L | Ding2008 | Intestines Cancer | 18428421, 18948947, 1905840, 8829653 | ENSP00000391478 | A138T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | D49Y | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | S95T | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | P177R | Ding2008, Sjoblom2006 | Intestines Cancer | 16959974, 18948947, 1905840, 8829653 | ENSP00000269305 | K305* | Ding2008 | Lung Cancer | 18948947 | ENSP00000269305 | E271Q | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | E349D | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | I195L | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | F385L | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | V157F | Ding2008, Sjoblom2006 | Liver Cancer | 1672732, 16959974, 18428421, 18948947, 1905840, 8829653, 21822264 | ENSP00000391478 | K139T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R249S | Sjoblom2006 | Liver Cancer | 1349102, 1694291, 16959974, 18428421, 1849234, 1905840, 8829653 | ENSP00000391478 | V157F | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | G334W | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | R306Q | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391127 | Y234C | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | A161T | Ding2008, BIOMART | Lung Cancer | 18428421, 18948947, 1905840, 8829653, 21930507, 21930502 | ENSP00000391478 | S314F | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | D324S | HPI | Other Cancer | 1905840 8829653 | ENSP00000398846 | F270L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | V272M | HPI | Neoplasms by Histologic Type | 1905840 8829653 19003964 | ENSP00000391478 | P152T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R213* | Ding2008 | Lung Cancer | 18428421, 18948947 | ENSP00000391478 | S241F | OMIM | Sarcoma | 1565143 8401536 | ENSP00000269305 | F109S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391127 | R273P | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | P318L | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | P47L | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | I195L | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | C242Y | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R280K | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000391478 | G154I | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | H178Y | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | P58T | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | Q167R | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | Q144R | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | P300S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | N288Y | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | S269I | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | E221Q | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | A78V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | D186V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R249S | Sjoblom2006 | Other Cancer(sporadic cancer) | 1349102, 1694291, 16959974, 18428421, 1849234, 1905840, 8829653 | ENSP00000269305 | W146* | COSMIC | Hepatocellular Carcinoma | 21822264 | ENSP00000269305 | P60Q | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | Y163S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | G244A | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | V157F | Ding2008, Sjoblom2006 | Other Cancer(sporadic cancer) | 1672732, 16959974, 18428421, 18948947, 1905840, 8829653 | ENSP00000269305 | C238F | Ding2008 | Other Cancer(sporadic cancer) | 18948947, 1905840, 8829653 | ENSP00000269305 | P58T | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | E198* | COSMIC | Ovarian Cancer | 21720365 | ENSP00000391478 | G112S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R249S | Sjoblom2006 | Lung Cancer | 1349102, 1694291, 16959974, 18428421, 1849234, 1905840, 8829653 | ENSP00000269305 | P190T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | A88V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | E68Q | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | V157F | OMIM | Hepatocellular Carcinoma | 1672732 | ENSP00000391478 | F54Y | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R175H | Ding2008, Sjoblom2006 | Lung Cancer | 16959974, 18428421, 18772890, 18948947 | ENSP00000269305 | R248Q | Sjoblom2006 | Central Nervous System Neoplasms | 1565143, 1683921, 16959974, 18428421, 18772890 | ENSP00000391478 | Y163C | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | Q192P | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R181S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R196* | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000269305 | G360V | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | L93P | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | P80S | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | W146S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | R306* | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | R209T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | T312S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | E56V | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | H296L | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | S241F | Sjoblom2006 | Liver Cancer | 1565143, 16959974, 18428421 | ENSP00000391478 | H233R | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | R280S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | K291Q | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | Y163S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R249S | Sjoblom2006 | Breast Cancer | 1349102, 1694291, 16959974, 18428421, 1849234, 1905840, 8829653 | ENSP00000269305 | D207Y | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | E285V | OMIM | Adrenal Gland Neoplasms | 18762572 | ENSP00000269305 | R174W | COSMIC | Hepatocellular Carcinoma | 21822264 | ENSP00000391478 | A69V | HPI | Other Cancer | 1905840 8829653 | ENSP00000398846 | E204* | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | E271V | HPI | Sarcoma | 1905840 8829653 | ENSP00000269305 | P92S | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R158F | Ding2008 | Other Cancer(sporadic cancer) | 18948947, 1905840, 8829653 | ENSP00000391478 | R213P | BIOMART | Colorectal Cancer | 21930507, 21930502 | ENSP00000269305 | S315P | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | H179R | Ding2008, BIOMART | Lung Cancer | 18428421, 18948947, 1905840, 8829653, 21930507, 21930502, 1905840, 8829653, 19665071 | ENSP00000269305 | Q165P | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | V272M | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000269305 | T284K | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | S303T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | L93P | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | H214fs*33 | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000269305 | T118R | HPI | Other Cancer | 1905840 8829653 | ENSP00000391127 | R282W | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000269305 | R282Q | HPI | Other Cancer | 1905840 8829653 18453682 20972454 19913028 18453682 | ENSP00000391478 | E11Q | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | L206M | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | S269I | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | V172I | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | P151S | OMIM | Breast Cancer | 1673792 8401536 | ENSP00000391478 | T256S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | M160V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R267W | Sjoblom2006 | Skin Cancer | 16959974, 18428421, 1905840, 8829653 | ENSP00000269305 | T140S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | A76T | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | S227P | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | K319R | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | G266T | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 | ENSP00000269305 | R306Q | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | S241F | Sjoblom2006 | Intestines Cancer | 1565143, 16959974, 18428421 | ENSP00000269305 | V272L | Ding2008 | Head and Neck Cancer | 18428421, 18948947 | ENSP00000398846 | Y236C | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | L344R | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | F109V | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 | ENSP00000398846 | E271Q | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | L145V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | G325V | OMIM | Lymphoma | 1565144 | ENSP00000391478 | L45M | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | E349* | COSMIC | Skin Cancer | 21984974 | ENSP00000391127 | H179Y | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | R282W | Ding2008 | Pancreatic Cancer | 1349175, 1565143, 1565144, 18428421, 18772890, 18948947, 8401536 | ENSP00000398846 | C275Y | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | I251V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | S215K | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | H297Y | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | N310T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | T304S | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | F212Y | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | F270L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | R181P | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000269305 | D208I | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | P301T | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | Y107H | HPI | Other Cancer | 1905840 8829653 | ENSP00000391127 | R248Q | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | L348S | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R248Q | Sjoblom2006 | Neoplasms by Histologic Type | 1565143, 1683921, 16959974, 18428421, 18772890 | ENSP00000398846 | D184H | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | P82S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | D352H | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | S6L | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | Q5H | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | S261R | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | D324S | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R175H | Ding2008, Sjoblom2006 | Intestines Cancer | 16959974, 18428421, 18772890, 18948947 | ENSP00000391478 | K291Q | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | P36L | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | C275S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | V216W | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | L299V | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | L289V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | P322R | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | G279W | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | E286L | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | P34L | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | A129V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | G245S | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | P60Q | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | K292G | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R158L | Ding2008 | Lung Cancer | 18428421, 18948947, 1905840, 8829653 | ENSP00000391478 | Y107X | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | G199V | HPI | Neoplasms by Histologic Type | 1905840 8829653 19825993 | ENSP00000269305 | P151R | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000398846 | F113V | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | G293W | HPI | Brain Cancer | 1905840 8829653 | ENSP00000269305 | C242F | Sjoblom2006 | Other Cancer(sporadic cancer) | 1394225, 16959974, 18428421, 1905840, 8829653 | ENSP00000269305 | S215I | Ding2008 | Other Cancer(sporadic cancer) | 18428421, 18948947, 1905840, 8829653 | ENSP00000269305 | G105C | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 | ENSP00000391478 | S46P | HPI | Neoplasms by Histologic Type | 1905840 8829653 19784392 19224462 18393224 | ENSP00000391478 | Q52H | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | I251V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | P222T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | P322R | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | A129fs*41 | COSMIC | Hepatocellular Carcinoma | 21822264 | ENSP00000269305 | T118fs*5 | COSMIC | Hepatocellular Carcinoma | 21822264 | ENSP00000391478 | T81I | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | H233R | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | R337H | OMIM | Adrenal Gland Neoplasms | 11481490 11753428 11600572 15121773 15741269 | ENSP00000391478 | G59N | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | G154I | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | R209Q | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 | ENSP00000391478 | C182Y | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | D61N | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | N311T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | C141Y | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000391478 | S392L | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | F134V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | S149T | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | L265R | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | T230S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R273L | Ding2008, Sjoblom2006 | Head and Neck Cancer | 16959974, 18428421, 18948947 | ENSP00000269305 | H193R | Sjoblom2006 | Intestines Cancer | 16959974, 18428421 | ENSP00000391478 | K320N | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | S241F | Sjoblom2006 | Central Nervous System Neoplasms | 1565143, 16959974, 18428421 | ENSP00000391478 | T329S | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | P67S | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | N210Y | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R337fs*8 | COSMIC | Ovarian Cancer | 21720365 | ENSP00000269305 | C242F | Sjoblom2006 | Lung Cancer | 1394225, 16959974, 18428421, 1905840, 8829653 | ENSP00000269305 | S392L | HPI | Other Cancer | 1905840 8829653 | ENSP00000391478 | V73M | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | K292G | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | F270Y | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | M243V | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | A39V | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R273H | Sjoblom2006 | Biliary Tract Cancer | 1565144, 16959974, 18428421, 18772890, 8423216 | ENSP00000269305 | P47L | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000269305 | R282W | Ding2008 | Central Nervous System Neoplasms | 1349175, 1565143, 1565144, 18428421, 18772890, 18948947, 8401536 | ENSP00000269305 | V272M | HPI | Neoplasms by Histologic Type | 1905840 8829653 19003964 | ENSP00000391478 | V147I | HPI | Neoplasms by Histologic Type | 1905840 8829653 | ENSP00000391478 | A63V | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | R175H | Ding2008, Sjoblom2006 | Renal Cancer | 16959974, 18428421, 18772890, 18948947 | ENSP00000269305 | V216M | COSMIC | Ovarian Cancer | 21720365 | ENSP00000269305 | V274D | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000269305 | A189V | HPI | Other Cancer | 1905840 8829653 | ENSP00000269305 | C275S | Ding2008 | Other Cancer(Sporadic cancers) | 18948947, 1905840, 8829653, 1905840, 8829653 |