| UniProt/SwissProt ID: | PRPK_HUMAN |
| Description: | TP53 regulating kinase [Source:HGNC Symbol;Acc:16197] |
| Location: | chr20 q13.12 |
| Node attribute: | kinase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T8 | AARATtPADGE | PhosphoSitePlus | |
| T135 | METEKtPQGLS | HPRD | |
| S34 | SSRFLsGLELV | PhosphoSitePlus | |
| T7 | PADG | HPRD | |
| S250 | RGRKRsMVG__ | PhosphoSitePlus | |
| S140 | TPQGLsNLAKT | Kdo | PhosphoSitePlus |
| T135 | METEKtPQGLS | Kdo | PhosphoSitePlus |
| Y201 | KGVDLyVLEKA | Kdo | PhosphoSitePlus |
| Dephosphorylation site |
| PRPK_HUMAN do not have dephosphorylation site. |
| Mutation site |
| PRPK_HUMAN do not have mutation site. |
| Differential expressed protein |
| PRPK_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PRPK_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PRPK_HUMAN | P53_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| PRPK_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0003824 | catalytic activity | IEA | molecular_function |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0002039 | p53 binding | IDA | molecular_function |
| GO:0016773 | phosphotransferase activity, alcohol group as acce | IEA | molecular_function |
| GO:0006468 | protein phosphorylation | IDA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0009103 | lipopolysaccharide biosynthetic process | IEA | biological_process |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0004674 | protein serine/threonine kinase activity | IDA | molecular_function |