Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SCN3B_HUMAN
Description:sodium channel, voltage-gated, type III, beta subunit [Source:HGNC Symbol;Acc:20665]
Location:chr11 q24.1
Node attribute:gene

Phosphorylation site
SCN3B_HUMAN do not have phosphorylation site.

Dephosphorylation site
SCN3B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000299333A195TSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000299333A195THPIColorectal Cancer16959974
ENSP00000299333Q89LSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000299333R132WCOSMICOvarian Cancer21720365
ENSP00000376523Q89LSjoblom2006Intestines Cancer16959974
ENSP00000376523A195TSjoblom2006Intestines Cancer16959974
ENSP00000299333G150ECOSMICMelanoma21499247
ENSP00000376523A195THPIColorectal Cancer16959974
ENSP00000376523Q89LHPIColorectal Cancer16959974
ENSP00000299333Q89LHPIColorectal Cancer16959974
ENSP00000299333E188KCOSMICOvarian Cancer21720365

Differential expressed protein
SCN3B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SCN3B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
P53_HUMANSCN3B_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
SCN3B_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0060373regulation of ventricular cardiac muscle cell membIMPbiological_process
GO:0019233sensory perception of painIEAbiological_process
GO:0086006voltage-gated sodium channel activity involved in IEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0035725sodium ion transmembrane transportIDAbiological_process
GO:2000649regulation of sodium ion transmembrane transporterIMPbiological_process
GO:0030018Z discIEAcellular_component
GO:0005886plasma membraneIDAcellular_component
GO:0072659protein localization to plasma membraneIMPbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0086014regulation of atrial cardiac muscle cell action poIMPbiological_process
GO:0006814sodium ion transportIEAbiological_process
GO:0001518voltage-gated sodium channel complexIDAcellular_component
GO:0010765positive regulation of sodium ion transportIDAbiological_process
GO:0086070SA node cell to atrial cardiac muscle cell communiIEAbiological_process
GO:0007399nervous system developmentIEAbiological_process
GO:0060048cardiac muscle contractionIMPbiological_process
GO:0086012membrane depolarization involved in regulation of IMPbiological_process
GO:0006814sodium ion transportNASbiological_process
GO:0060371regulation of atrial cardiac muscle cell membrane IEAbiological_process
GO:0005248voltage-gated sodium channel activityNASmolecular_function
GO:0086002regulation of cardiac muscle cell action potentialIMPbiological_process
GO:0086010membrane depolarization involved in regulation of IDAbiological_process
GO:0044325ion channel bindingIPImolecular_function
GO:0061337cardiac conductionIEAbiological_process
GO:0017080sodium channel regulator activityIMPmolecular_function
GO:0086005regulation of ventricular cardiac muscle cell actiIEAbiological_process
GO:0051899membrane depolarizationIDAbiological_process
GO:0086091regulation of heart rate by cardiac conductionIMPbiological_process
GO:0010460positive regulation of heart rateIEAbiological_process
GO:0007411axon guidanceTASbiological_process


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