Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:BBC3_HUMAN
Description:BCL2 binding component 3 [Source:HGNC Symbol;Acc:17868]
Location:chr19 q13.32
Node attribute:TF; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S96DGPQPsLSLAEPhosphoSitePlus
S10RQEGSsPEPVEPhosphoSitePlus
S106EQHLEsPVPSAPhosphoSitePlus

Dephosphorylation site
BBC3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000341155Q27EBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
BBC3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
BBC3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
BBC3_HUMANTPIP1_HUMANTF -> target geneKEGG
BBC3_HUMANP53_HUMANTF -> target geneKEGG
P53_HUMANBBC3_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05162Measles
hsa05016Huntington's disease
hsa04115p53 signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005829cytosolTAScellular_component
GO:0006917induction of apoptosisIDAbiological_process
GO:0051209release of sequestered calcium ion into cytosolIDAbiological_process
GO:0032464positive regulation of protein homooligomerizationIDAbiological_process
GO:0006919activation of cysteine-type endopeptidase activityIDAbiological_process
GO:0043525positive regulation of neuron apoptotic processISSbiological_process
GO:0006915apoptotic processIDAbiological_process
GO:0005741mitochondrial outer membraneTAScellular_component
GO:0071456cellular response to hypoxiaIEPbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0042771intrinsic apoptotic signaling pathway in response ISSbiological_process
GO:0001836release of cytochrome c from mitochondriaIDAbiological_process
GO:1900740positive regulation of protein insertion into mitoIDAbiological_process
GO:2001244positive regulation of intrinsic apoptotic signaliIMPbiological_process
GO:0005739mitochondrionIDAcellular_component
GO:0034976response to endoplasmic reticulum stressIDAbiological_process
GO:0090200positive regulation of release of cytochrome c froIDAbiological_process
GO:0008340determination of adult lifespanISSbiological_process
GO:0045926negative regulation of growthIMPbiological_process
GO:0070245positive regulation of thymocyte apoptotic processISSbiological_process
GO:2001056positive regulation of cysteine-type endopeptidaseISSbiological_process
GO:0070059intrinsic apoptotic signaling pathway in response ISSbiological_process
GO:0032471reduction of endoplasmic reticulum calcium ion conIDAbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23