Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PAX5_HUMAN
Description:paired box 5 [Source:HGNC Symbol;Acc:8619]
Location:chr9 p13.2
Node attribute:gene; TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S206EGIQEsPVPNGPhosphoSitePlus
S168SVTQVsSVSTDPhosphoSitePlus
Y299PGPQSyPIVTGPhosphoSitePlus
Y73ILGRYyETGSIPAXPhosphoSitePlus
Y7DLEKNyPTPRTPhosphoSitePlus
S180AGSSYsISGILPhosphoSitePlus
S298VPGPQsYPIVTPhosphoSitePlus
Y179SAGSSySISGIPhosphoSitePlus

Dephosphorylation site
PAX5_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000350844R59GCOSMICLymphoma19129520
ENSP00000350844Y346CCOSMICCentral Nervous System Neoplasms18772890
ENSP00000350844V151ICOSMICLymphoma19129520
ENSP00000350844V26GCOSMICLymphoma17344859
ENSP00000350844G314WCOSMICLung Cancer20668451
ENSP00000350844G24RCOSMICLymphoma19129520
ENSP00000350844D53VCOSMICLymphoma19129520
ENSP00000350844P80RCOSMICLymphoma19129520
ENSP00000350844P320LCOSMICLung Cancer20668451
ENSP00000350844P34QCOSMICLymphoma17344859
ENSP00000350844I301TCOSMICLymphoma19129520
ENSP00000350844I139TCOSMICLymphoma19129520
ENSP00000350844N355HCOSMICLung Cancer20668451
ENSP00000350844T75RCOSMICLymphoma19129520
ENSP00000350844S213LCOSMICLymphoma19129520
ENSP00000350844G338WCOSMICLymphoma17344859

Differential expressed protein
PAX5_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PAX5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PAX5_HUMANCD19_HUMANTF -> target geneTRANSFAC
PRDM1_HUMANPAX5_HUMANTF -> target geneTRANSFAC
PAX5_HUMANP53_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
PAX5_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007275multicellular organismal developmentTASbiological_process
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0007283spermatogenesisIEAbiological_process
GO:0007399nervous system developmentIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0006959humoral immune responseTASbiological_process
GO:0009887organ morphogenesisTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0051573negative regulation of histone H3-K9 methylationIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0030154cell differentiationIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function


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