Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:VRK1_HUMAN
Description:vaccinia related kinase 1 [Source:HGNC Symbol;Acc:12718]
Location:chr14 q32.2
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S158TVLQLsLRILDHPRD
T378TEWSNtQTEEAPhosphoSitePlus; HPRD
S342GKLDLsVVENGPLK3HPRD
T305AKYMEtVKLLDHPRD; phosphoELM
T153RFSRKtVLQLSHPRD
S158TVLQLsLRILDPkinasePhosphoSitePlus
T355KAKTItKKRKKPhosphoSitePlus; HPRD; phosphoELM
S376EDTEWsNTQTEPhosphoSitePlus; HPRD
T380WSNTQtEEAIQPhosphoSitePlus
T390QTRSRtRKRVHPRD; phosphoELM
T153RFSRKtVLQLSPkinasePhosphoSitePlus
S342GKLDLsVVENGPhosphoSitePlus

Dephosphorylation site
VRK1_HUMAN do not have dephosphorylation site.

Mutation site
VRK1_HUMAN do not have mutation site.

Differential expressed protein
VRK1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
VRK1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
VRK1_HUMANXRCC1_HUMANkinase -> substrateRobert H Newman (2013)
VRK1_HUMANP53_HUMANkinase -> substrateHPRD; RegPhos
VRK1_HUMANMRF_HUMANkinase -> substrateRobert H Newman (2013)
VRK1_HUMANHSFX1_HUMANkinase -> substrateRobert H Newman (2013)
VRK1_HUMANATF2_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
VRK1_HUMANJUN_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
VRK1_HUMANTOX_HUMANkinase -> substrateRobert H Newman (2013)
PLK3_HUMANVRK1_HUMANkinase -> substrateHPRD
VRK1_HUMANNFAC4_HUMANkinase -> substrateRobert H Newman (2013)
VRK1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
VRK1_HUMANAIRE_HUMANkinase -> substrateRobert H Newman (2013)
VRK1_HUMANNDF1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
VRK1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005634nucleusIDAcellular_component
GO:0006468protein phosphorylationTASbiological_process
GO:0005634nucleusIEAcellular_component
GO:0046777protein autophosphorylationIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0046777protein autophosphorylationIDAbiological_process
GO:0005795Golgi stackIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0007067mitosisIEAbiological_process
GO:0005730nucleolusIDAcellular_component
GO:0004672protein kinase activityIEAmolecular_function
GO:0005819spindleIEAcellular_component
GO:0051301cell divisionIEAbiological_process
GO:0004674protein serine/threonine kinase activityIDAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0090166Golgi disassemblyIDAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0042802identical protein bindingIPImolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function


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