Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NFIC_HUMAN
Description:nuclear factor I/C (CCAAT-binding transcription factor) [Source:HGNC Symbol;Acc:7786]
Location:chr19 p13.3
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S294EDVDTsPGGDYHPRD; phosphoELM
S305YTSPSsPTSSSHPRD; phosphoELM
Y2SPLCHPRD
Y41ARKRKyFKKHEPhosphoSitePlus
S487SPANRsFVGLGCTF_NFIPhosphoSitePlus
S304YYTSPsSPTSSHPRD; phosphoELM
S337KSPFNsPSPQDHPRD; phosphoELM
S339PFNSPsPQDSPCTF_NFIPhosphoSitePlus; SysPTM
S333TEMDKsPFNSPCTF_NFIPhosphoSitePlus
S304YYTSPsSPTSSCTF_NFIPhosphoSitePlus
T237IQVSRtPVVTGHPRD
S343PSPQDsPRLSSCTF_NFIPhosphoSitePlus
T237IQVSRtPVVTGCTF_NFIPhosphoSitePlus
S366SGIARsPHPSSHPRD
S192RDAEQsGSPRTHPRD; phosphoELM
S322MEGGIsSPVKKCTF_NFIPhosphoSitePlus
S333TEMDKsPFNSPHPRD; phosphoELM
S286RHKSGsMEEDVHPRD
S4__MYSsPLCLTPhosphoSitePlus; SysPTM
S279TSSSGsKRHKSCTF_NFIPhosphoSitePlus
T270TGLRRtLPSTSCTF_NFIPhosphoSitePlus
Y476PTSPSySPPDTCTF_NFIPhosphoSitePlus
T472GATSPtSPSYSCTF_NFIPhosphoSitePlus
S284SKRHKsGSMEECTF_NFIPhosphoSitePlus
S339PFNSPsPQDSPHPRD; phosphoELM; SysPTM
T314SSRNWtEDMEGCTF_NFIPhosphoSitePlus
S427GPLNGsGQLKMCTF_NFIPhosphoSitePlus
S482SPPDTsPANRSCTF_NFIPhosphoSitePlus
S294EDVDTsPGGDYCTF_NFIPhosphoSitePlus
T481YSPPDtSPANRCTF_NFIPhosphoSitePlus
S343PSPQDsPRLSSHPRD; phosphoELM
S473ATSPTsPSYSPCTF_NFIPhosphoSitePlus
S275TLPSTsSSGSKCTF_NFIPhosphoSitePlus
S366SGIARsPHPSSCTF_NFIPhosphoSitePlus
S3PLCLHPRD
S4LCLTHPRD; phosphoELM; SysPTM
S337KSPFNsPSPQDCTF_NFIPhosphoSitePlus
S322MEGGIsSPVKKHPRD; phosphoELM
S194AEQSGsPRTGMPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S323EGGISsPVKKTCTF_NFIPhosphoSitePlus; SysPTM
S305YTSPSsPTSSSCTF_NFIPhosphoSitePlus
T328SPVKKtEMDKSHPRD; phosphoELM
S323EGGISsPVKKTHPRD; phosphoELM; SysPTM

Dephosphorylation site
NFIC_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000396843D250NCOSMICHead and Neck Cancer21798893

Differential expressed protein
NFIC_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NFIC_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NFIC_HUMANU627C_HUMANTF -> target geneTRANSFAC
NFIC_HUMANHBA_HUMANTF -> target geneTRANSFAC
NFIC_HUMANGLHA_HUMANTF -> target geneTRANSFAC
NFIC_HUMANAPOB_HUMANTF -> target geneTRANSFAC
NFIC_HUMANGFAP_HUMANTF -> target geneTRANSFAC
NFIC_HUMANP53_HUMANTF -> target geneTRANSFAC
NFIC_HUMANFINC_HUMANTF -> target geneTRANSFAC
NFIC_HUMANSOMA_HUMANTF -> target geneTRANSFAC
NFIC_HUMANRASN_HUMANTF -> target geneTRANSFAC
NFIC_HUMANHMGB1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
NFIC_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000122negative regulation of transcription from RNA polyIGIbiological_process
GO:0005622intracellularIEAcellular_component
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0007179transforming growth factor beta receptor signalingIEAbiological_process
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0003700sequence-specific DNA binding transcription factorIDAmolecular_function
GO:0006260DNA replicationIEAbiological_process
GO:0005667transcription factor complexIEAcellular_component


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