Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PIDD_HUMAN
Description:p53-induced death domain protein [Source:HGNC Symbol;Acc:16491]
Location:chr11 p15.5
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T4__MAAtVEGPEPhosphoSitePlus
T788ETGFLtQSNLLPhosphoSitePlus
Y814HLGVSyREVQRDeathPhosphoSitePlus
T485FPPGAtEEPRRHPRD
T485FPPGAtEEPRRZU5PhosphoSitePlus

Dephosphorylation site
PIDD_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000337797P210LCOSMICSkin Cancer21984974
ENSP00000416801D200HBIOMARTBreast Cancer21930507, 21930502
ENSP00000337797M493VCOSMICHead and Neck Cancer21798893
ENSP00000337797D200HBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
PIDD_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PIDD_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
P53_HUMANPIDD_HUMANTF -> target geneKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04115p53 signaling pathway
hsa04064NF-kappa B signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIEAcellular_component
GO:0005737cytoplasmIMPcellular_component
GO:0005634nucleusIMPcellular_component
GO:0006974response to DNA damage stimulusIDAbiological_process
GO:0006915apoptotic processIEAbiological_process
GO:0005123death receptor bindingTASmolecular_function
GO:0043066negative regulation of apoptotic processIMPbiological_process
GO:0006977DNA damage response, signal transduction by p53 clIMPbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0007165signal transductionTASbiological_process


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