Phosphorylation

You are querying signaling transduction network mediated by ACM3_HUMAN in Intestines Cancer.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	CLAT_HUMAN	ACM3_HUMAN	ligand -> receptor	HPMR
2	ACM3_HUMAN	GNAQ_HUMAN	GPCR -> Gprotein	gpDB
3	ACM3_HUMAN	GNA11_HUMAN	GPCR -> Gprotein	gpDB
4	ACM3_HUMAN	GNA13_HUMAN	GPCR -> Gprotein	gpDB
5	GNAQ_HUMAN	BTK_HUMAN	Gprotein -> effector	gpDB
6	GNAQ_HUMAN	PK3CA_HUMAN	Gprotein -> effector	gpDB
7	GNAQ_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
8	GNAQ_HUMAN	KPCD1_HUMAN	Gprotein -> effector	gpDB
9	GNA11_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
10	GNA13_HUMAN	KPCD1_HUMAN	Gprotein -> effector	gpDB
11	BTK_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
12	BTK_HUMAN	SMAD3_HUMAN	kinase -> substrate	Robert H Newman (2013)
13	BTK_HUMAN	MK01_HUMAN	kinase -> substrate	Robert H Newman (2013)
14	BTK_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
15	PK3CA_HUMAN	KS6B1_HUMAN	kinase -> substrate	HPRD
16	BTK_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
17	ARBK1_HUMAN	P53_HUMAN	kinase -> substrate	Robert H Newman (2013)
18	KPCD1_HUMAN	KSYK_HUMAN	kinase -> substrate	NetPath
19	BTK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
20	BTK_HUMAN	STA5B_HUMAN	kinase -> substrate	Robert H Newman (2013)
21	BTK_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
22	BTK_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
23	BTK_HUMAN	STA5A_HUMAN	kinase -> substrate	HPRD; RegPhos
24	BTK_HUMAN	ITK_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
25	BTK_HUMAN	CDK9_HUMAN	kinase -> substrate	Robert H Newman (2013)
26	BTK_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
27	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
28	MK01_HUMAN	SP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
29	MK01_HUMAN	BCL6_HUMAN	kinase -> substrate	NetPath
30	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
31	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
32	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
33	KS6B1_HUMAN	HSF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
34	MK01_HUMAN	GSK3B_HUMAN	kinase -> substrate	Robert H Newman (2013)
35	MK01_HUMAN	SOS1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
36	KS6A2_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
37	KS6A2_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
38	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
39	MK01_HUMAN	PRGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
40	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
41	KS6A2_HUMAN	SRF_HUMAN	kinase -> substrate	RegPhos
42	MK01_HUMAN	STF1_HUMAN	kinase -> substrate	HPRD
43	KSYK_HUMAN	KS6A1_HUMAN	kinase -> substrate	NetPath
44	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
45	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
46	MK01_HUMAN	SRBP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
47	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
48	MK01_HUMAN	STK16_HUMAN	kinase -> substrate	Robert H Newman (2013)
49	KS6A2_HUMAN	FOS_HUMAN	kinase -> substrate	RegPhos
50	MK01_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
51	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
52	MK01_HUMAN	ELK1_HUMAN	kinase -> substrate	NetPath
53	P53_HUMAN	ATF3_HUMAN	TF -> target gene	TRANSFAC
54	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
55	KS6B1_HUMAN	MTOR_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
56	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
57	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
58	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
59	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
60	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	MK01_HUMAN	MITF_HUMAN	kinase -> substrate	NetPath
62	SMAD3_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
63	MK01_HUMAN	ELK4_HUMAN	kinase -> substrate	KEGG
64	KSYK_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
65	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
66	KS6A2_HUMAN	KS6A1_HUMAN	kinase -> substrate	RegPhos
67	KS6B1_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
68	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
69	KSYK_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
70	MK01_HUMAN	JUN_HUMAN	kinase -> substrate	KEGG
71	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
72	MK01_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
73	MK01_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD
74	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
75	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
76	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
77	MK01_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD
78	KS6A2_HUMAN	NR4A1_HUMAN	kinase -> substrate	RegPhos
79	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
80	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
81	MK01_HUMAN	MYC_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
82	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
83	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
84	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
85	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
86	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
87	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
88	MK01_HUMAN	RXRA_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
89	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
90	MK01_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
91	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
92	MK01_HUMAN	CEBPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
93	MK01_HUMAN	PPARA_HUMAN	kinase -> substrate	HPRD
94	MK01_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
95	MK01_HUMAN	MP2K1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
96	STA5A_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
97	ITK_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
98	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
99	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
100	MK01_HUMAN	THB_HUMAN	kinase -> substrate	Robert H Newman (2013)
101	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
102	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
103	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
104	MK01_HUMAN	SRBP2_HUMAN	kinase -> substrate	Robert H Newman (2013)
105	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
106	MK01_HUMAN	SMAD4_HUMAN	kinase -> substrate	HPRD
107	MK01_HUMAN	FOS_HUMAN	kinase -> substrate; other	KEGG
108	P53_HUMAN	P73_HUMAN	TF -> target gene	KEGG; TRANSFAC
109	KS6B1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
110	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
111	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
112	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
113	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
114	KS6A2_HUMAN	CEBPB_HUMAN	kinase -> substrate	RegPhos
115	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
116	CDK9_HUMAN	CHK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
117	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
118	MK01_HUMAN	TFE2_HUMAN	kinase -> substrate	HPRD; NetPath
119	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
120	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
121	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
122	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
123	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
125	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
126	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
127	MK01_HUMAN	PKN1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
128	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
129	MK01_HUMAN	MYB_HUMAN	kinase -> substrate	HPRD
130	KS6A2_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
131	KS6A2_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
132	KS6B1_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
133	MK01_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD
134	MK01_HUMAN	CEBPB_HUMAN	kinase -> substrate	HPRD
135	SP1_HUMAN	PHX2A_HUMAN	TF -> target gene	TRANSFAC
136	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
137	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
138	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
139	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
140	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
141	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
142	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
143	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
144	STK16_HUMAN	IRF5_HUMAN	kinase -> substrate	Robert H Newman (2013)
145	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
146	SP1_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
147	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
148	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
149	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
150	SP1_HUMAN	AP2C_HUMAN	TF -> target gene	TRANSFAC
151	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
152	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
153	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
154	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
155	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
156	SP1_HUMAN	MAZ_HUMAN	TF -> target gene	TRANSFAC
157	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
158	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
159	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
160	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
161	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
162	SP1_HUMAN	RARA_HUMAN	TF -> target gene	TRANSFAC
163	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
164	SP1_HUMAN	CDK2_HUMAN	TF -> target gene	TRANSFAC
165	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
166	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
167	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
168	SP1_HUMAN	SP3_HUMAN	TF -> target gene	TRANSFAC
169	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
170	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
171	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
172	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
173	SP1_HUMAN	TGFR2_HUMAN	TF -> target gene	TRANSFAC
174	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
175	SP1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
176	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
177	CHK2_HUMAN	E2F1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
178	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
179	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
180	SP1_HUMAN	HNF4A_HUMAN	TF -> target gene	TRANSFAC
181	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
182	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
183	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
184	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
185	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
186	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
187	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
188	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
189	CDK2_HUMAN	TFDP1_HUMAN	kinase -> substrate	RegPhos
190	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
191	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
192	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
193	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
194	TGFR2_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
195	CDK2_HUMAN	NFYA_HUMAN	kinase -> substrate	HPRD
196	ACM3_HUMAN	GNA12_HUMAN	GPCR -> Gprotein	gpDB

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network