Phosphorylation

You are querying signaling transduction network mediated by 5HT2B_HUMAN in Intestines Cancer.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	TPH1_HUMAN	5HT2B_HUMAN	ligand -> receptor	HPMR
2	5HT2B_HUMAN	GNAQ_HUMAN	GPCR -> Gprotein	gpDB
3	5HT2B_HUMAN	GNA11_HUMAN	GPCR -> Gprotein	gpDB
4	GNAQ_HUMAN	BTK_HUMAN	Gprotein -> effector	gpDB
5	GNAQ_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
6	GNAQ_HUMAN	PK3CA_HUMAN	Gprotein -> effector	gpDB
7	GNAQ_HUMAN	KPCD1_HUMAN	Gprotein -> effector	gpDB
8	GNA11_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
9	BTK_HUMAN	MK01_HUMAN	kinase -> substrate	Robert H Newman (2013)
10	ARBK1_HUMAN	P53_HUMAN	kinase -> substrate	Robert H Newman (2013)
11	BTK_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
12	BTK_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
13	BTK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
14	PK3CA_HUMAN	KS6B1_HUMAN	kinase -> substrate	HPRD
15	BTK_HUMAN	STA5A_HUMAN	kinase -> substrate	HPRD; RegPhos
16	BTK_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
17	KPCD1_HUMAN	KSYK_HUMAN	kinase -> substrate	NetPath
18	BTK_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
19	BTK_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
20	BTK_HUMAN	CDK9_HUMAN	kinase -> substrate	Robert H Newman (2013)
21	BTK_HUMAN	SMAD3_HUMAN	kinase -> substrate	Robert H Newman (2013)
22	BTK_HUMAN	STA5B_HUMAN	kinase -> substrate	Robert H Newman (2013)
23	BTK_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
24	BTK_HUMAN	ITK_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
25	MK01_HUMAN	JUN_HUMAN	kinase -> substrate	KEGG
26	P53_HUMAN	ATF3_HUMAN	TF -> target gene	TRANSFAC
27	KS6A2_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
28	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
29	KS6A2_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
30	KS6A2_HUMAN	SRF_HUMAN	kinase -> substrate	RegPhos
31	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
32	MK01_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD
33	KS6B1_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
34	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
35	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
36	STA5A_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
37	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
38	MK01_HUMAN	SP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
39	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
40	MK01_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
41	MK01_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
42	MK01_HUMAN	STK16_HUMAN	kinase -> substrate	Robert H Newman (2013)
43	KS6A2_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
44	MK01_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
45	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
46	KS6B1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
47	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
48	KSYK_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
49	MK01_HUMAN	ELK1_HUMAN	kinase -> substrate	NetPath
50	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
51	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
52	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
53	KS6A2_HUMAN	KS6A1_HUMAN	kinase -> substrate	RegPhos
54	KSYK_HUMAN	KS6A1_HUMAN	kinase -> substrate	NetPath
55	KS6B1_HUMAN	HSF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
56	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
57	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
58	MK01_HUMAN	FOS_HUMAN	kinase -> substrate; other	KEGG
59	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
60	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
62	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
63	MK01_HUMAN	ELK4_HUMAN	kinase -> substrate	KEGG
64	MK01_HUMAN	THB_HUMAN	kinase -> substrate	Robert H Newman (2013)
65	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
66	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
67	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
68	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
69	MK01_HUMAN	MYC_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
70	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
71	MK01_HUMAN	MYB_HUMAN	kinase -> substrate	HPRD
72	MK01_HUMAN	STF1_HUMAN	kinase -> substrate	HPRD
73	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
74	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
75	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
76	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
77	P53_HUMAN	P73_HUMAN	TF -> target gene	KEGG; TRANSFAC
78	CDK9_HUMAN	CHK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
79	MK01_HUMAN	PPARA_HUMAN	kinase -> substrate	HPRD
80	SMAD3_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
81	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
82	KS6A2_HUMAN	CEBPB_HUMAN	kinase -> substrate	RegPhos
83	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
84	MK01_HUMAN	PRGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
85	MK01_HUMAN	MITF_HUMAN	kinase -> substrate	NetPath
86	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
87	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
88	MK01_HUMAN	TFE2_HUMAN	kinase -> substrate	HPRD; NetPath
89	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
90	MK01_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
91	MK01_HUMAN	BCL6_HUMAN	kinase -> substrate	NetPath
92	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
93	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
94	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
95	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
96	MK01_HUMAN	PKN1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
97	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
98	KS6B1_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
99	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
100	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
101	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
102	MK01_HUMAN	SRBP2_HUMAN	kinase -> substrate	Robert H Newman (2013)
103	KSYK_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
104	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
105	MK01_HUMAN	GSK3B_HUMAN	kinase -> substrate	Robert H Newman (2013)
106	MK01_HUMAN	SRBP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
107	MK01_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD
108	MK01_HUMAN	CEBPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
109	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
110	MK01_HUMAN	MP2K1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
111	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
112	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
113	KS6B1_HUMAN	MTOR_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
114	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
115	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
116	MK01_HUMAN	RXRA_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
117	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
118	KS6A2_HUMAN	NR4A1_HUMAN	kinase -> substrate	RegPhos
119	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
120	KS6A2_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
121	MK01_HUMAN	CEBPB_HUMAN	kinase -> substrate	HPRD
122	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
123	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	KS6A2_HUMAN	FOS_HUMAN	kinase -> substrate	RegPhos
125	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
126	MK01_HUMAN	SMAD4_HUMAN	kinase -> substrate	HPRD
127	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
128	MK01_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD
129	MK01_HUMAN	SOS1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
130	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
131	ITK_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
132	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
133	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
134	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
135	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
136	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
137	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
138	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
139	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
140	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
141	SP1_HUMAN	HNF4A_HUMAN	TF -> target gene	TRANSFAC
142	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
143	STK16_HUMAN	IRF5_HUMAN	kinase -> substrate	Robert H Newman (2013)
144	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
145	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
146	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
147	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
148	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
149	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
150	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
151	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
152	SP1_HUMAN	PHX2A_HUMAN	TF -> target gene	TRANSFAC
153	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
154	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
155	CHK2_HUMAN	E2F1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
156	SP1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
157	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
158	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
159	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
160	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
161	SP1_HUMAN	AP2C_HUMAN	TF -> target gene	TRANSFAC
162	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
163	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
164	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
165	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
166	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
167	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
168	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
169	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
170	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
171	SP1_HUMAN	TGFR2_HUMAN	TF -> target gene	TRANSFAC
172	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
173	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
174	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
175	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
176	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
177	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
178	SP1_HUMAN	MAZ_HUMAN	TF -> target gene	TRANSFAC
179	SP1_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
180	SP1_HUMAN	CDK2_HUMAN	TF -> target gene	TRANSFAC
181	SP1_HUMAN	RARA_HUMAN	TF -> target gene	TRANSFAC
182	SP1_HUMAN	SP3_HUMAN	TF -> target gene	TRANSFAC
183	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
184	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
185	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
186	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
187	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
188	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
189	TGFR2_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
190	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
191	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
192	CDK2_HUMAN	TFDP1_HUMAN	kinase -> substrate	RegPhos
193	CDK2_HUMAN	NFYA_HUMAN	kinase -> substrate	HPRD

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network