Phosphorylation

You are querying signaling transduction network mediated by V1BR_HUMAN in Intestines Cancer.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	NEU2_HUMAN	V1BR_HUMAN	ligand -> receptor	HPMR
2	V1BR_HUMAN	GNAQ_HUMAN	GPCR -> Gprotein	gpDB
3	V1BR_HUMAN	GNA11_HUMAN	GPCR -> Gprotein	gpDB
4	GNAQ_HUMAN	BTK_HUMAN	Gprotein -> effector	gpDB
5	GNA11_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
6	GNAQ_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
7	GNAQ_HUMAN	KPCD1_HUMAN	Gprotein -> effector	gpDB
8	GNAQ_HUMAN	PK3CA_HUMAN	Gprotein -> effector	gpDB
9	BTK_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
10	BTK_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
11	BTK_HUMAN	MK01_HUMAN	kinase -> substrate	Robert H Newman (2013)
12	BTK_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
13	BTK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
14	ARBK1_HUMAN	P53_HUMAN	kinase -> substrate	Robert H Newman (2013)
15	BTK_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
16	KPCD1_HUMAN	KSYK_HUMAN	kinase -> substrate	NetPath
17	BTK_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
18	BTK_HUMAN	SMAD3_HUMAN	kinase -> substrate	Robert H Newman (2013)
19	PK3CA_HUMAN	KS6B1_HUMAN	kinase -> substrate	HPRD
20	BTK_HUMAN	CDK9_HUMAN	kinase -> substrate	Robert H Newman (2013)
21	BTK_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
22	BTK_HUMAN	STA5A_HUMAN	kinase -> substrate	HPRD; RegPhos
23	BTK_HUMAN	STA5B_HUMAN	kinase -> substrate	Robert H Newman (2013)
24	BTK_HUMAN	ITK_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
25	KS6A2_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
26	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
27	MK01_HUMAN	SP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
28	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
29	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
30	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
31	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
32	MK01_HUMAN	STK16_HUMAN	kinase -> substrate	Robert H Newman (2013)
33	P53_HUMAN	ATF3_HUMAN	TF -> target gene	TRANSFAC
34	MK01_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
35	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
36	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
37	P53_HUMAN	P73_HUMAN	TF -> target gene	KEGG; TRANSFAC
38	MK01_HUMAN	SMAD4_HUMAN	kinase -> substrate	HPRD
39	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
40	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
41	KS6A2_HUMAN	CEBPB_HUMAN	kinase -> substrate	RegPhos
42	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
43	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
44	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
45	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
46	MK01_HUMAN	SOS1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
47	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
48	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
49	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
50	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
51	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
52	KSYK_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
53	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
54	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
55	KS6A2_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
56	MK01_HUMAN	RXRA_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
57	MK01_HUMAN	PPARA_HUMAN	kinase -> substrate	HPRD
58	MK01_HUMAN	MYB_HUMAN	kinase -> substrate	HPRD
59	MK01_HUMAN	PRGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
60	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	SMAD3_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
62	MK01_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
63	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
64	MK01_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD
65	KS6A2_HUMAN	SRF_HUMAN	kinase -> substrate	RegPhos
66	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
67	MK01_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD
68	MK01_HUMAN	MYC_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
69	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
70	KS6B1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
71	MK01_HUMAN	THB_HUMAN	kinase -> substrate	Robert H Newman (2013)
72	CDK9_HUMAN	CHK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
73	MK01_HUMAN	ELK4_HUMAN	kinase -> substrate	KEGG
74	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
75	MK01_HUMAN	PKN1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
76	KS6B1_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
77	MK01_HUMAN	JUN_HUMAN	kinase -> substrate	KEGG
78	MK01_HUMAN	TFE2_HUMAN	kinase -> substrate	HPRD; NetPath
79	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
80	MK01_HUMAN	MP2K1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
81	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
82	KS6A2_HUMAN	KS6A1_HUMAN	kinase -> substrate	RegPhos
83	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
84	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
85	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
86	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
87	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
88	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
89	KSYK_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
90	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
91	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
92	KS6B1_HUMAN	HSF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
93	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
94	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
95	MK01_HUMAN	SRBP2_HUMAN	kinase -> substrate	Robert H Newman (2013)
96	MK01_HUMAN	GSK3B_HUMAN	kinase -> substrate	Robert H Newman (2013)
97	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
98	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
99	STA5A_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
100	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
101	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
102	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
103	MK01_HUMAN	BCL6_HUMAN	kinase -> substrate	NetPath
104	MK01_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
105	MK01_HUMAN	CEBPB_HUMAN	kinase -> substrate	HPRD
106	MK01_HUMAN	ELK1_HUMAN	kinase -> substrate	NetPath
107	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
108	MK01_HUMAN	STF1_HUMAN	kinase -> substrate	HPRD
109	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
110	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
111	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
112	MK01_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
113	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
114	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
115	MK01_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD
116	MK01_HUMAN	MITF_HUMAN	kinase -> substrate	NetPath
117	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
118	KS6A2_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
119	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
120	KSYK_HUMAN	KS6A1_HUMAN	kinase -> substrate	NetPath
121	ITK_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
122	KS6A2_HUMAN	FOS_HUMAN	kinase -> substrate	RegPhos
123	MK01_HUMAN	CEBPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	MK01_HUMAN	SRBP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
125	KS6A2_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
126	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
127	MK01_HUMAN	FOS_HUMAN	kinase -> substrate; other	KEGG
128	KS6A2_HUMAN	NR4A1_HUMAN	kinase -> substrate	RegPhos
129	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
130	KS6B1_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
131	KS6B1_HUMAN	MTOR_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
132	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
133	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
134	SP1_HUMAN	CDK2_HUMAN	TF -> target gene	TRANSFAC
135	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
136	SP1_HUMAN	SP3_HUMAN	TF -> target gene	TRANSFAC
137	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
138	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
139	STK16_HUMAN	IRF5_HUMAN	kinase -> substrate	Robert H Newman (2013)
140	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
141	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
142	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
143	SP1_HUMAN	PHX2A_HUMAN	TF -> target gene	TRANSFAC
144	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
145	SP1_HUMAN	MAZ_HUMAN	TF -> target gene	TRANSFAC
146	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
147	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
148	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
149	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
150	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
151	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
152	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
153	SP1_HUMAN	RARA_HUMAN	TF -> target gene	TRANSFAC
154	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
155	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
156	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
157	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
158	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
159	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
160	SP1_HUMAN	AP2C_HUMAN	TF -> target gene	TRANSFAC
161	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
162	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
163	CHK2_HUMAN	E2F1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
164	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
165	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
166	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
167	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
168	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
169	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
170	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
171	SP1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
172	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
173	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
174	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
175	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
176	SP1_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
177	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
178	SP1_HUMAN	TGFR2_HUMAN	TF -> target gene	TRANSFAC
179	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
180	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
181	SP1_HUMAN	HNF4A_HUMAN	TF -> target gene	TRANSFAC
182	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
183	CDK2_HUMAN	TFDP1_HUMAN	kinase -> substrate	RegPhos
184	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
185	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
186	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
187	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
188	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
189	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
190	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
191	TGFR2_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
192	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
193	CDK2_HUMAN	NFYA_HUMAN	kinase -> substrate	HPRD

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network