Phosphorylation

You are querying signaling transduction network mediated by MCHR2_HUMAN in Intestines Cancer.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	MCH_HUMAN	MCHR2_HUMAN	ligand -> receptor	HPMR
2	MCHR2_HUMAN	GNAQ_HUMAN	GPCR -> Gprotein	gpDB
3	MCHR2_HUMAN	GNA11_HUMAN	GPCR -> Gprotein	gpDB
4	GNAQ_HUMAN	BTK_HUMAN	Gprotein -> effector	gpDB
5	GNA11_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
6	GNAQ_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
7	GNAQ_HUMAN	PK3CA_HUMAN	Gprotein -> effector	gpDB
8	GNAQ_HUMAN	KPCD1_HUMAN	Gprotein -> effector	gpDB
9	BTK_HUMAN	MK01_HUMAN	kinase -> substrate	Robert H Newman (2013)
10	BTK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
11	BTK_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
12	BTK_HUMAN	STA5B_HUMAN	kinase -> substrate	Robert H Newman (2013)
13	ARBK1_HUMAN	P53_HUMAN	kinase -> substrate	Robert H Newman (2013)
14	BTK_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
15	BTK_HUMAN	STA5A_HUMAN	kinase -> substrate	HPRD; RegPhos
16	BTK_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
17	BTK_HUMAN	SMAD3_HUMAN	kinase -> substrate	Robert H Newman (2013)
18	PK3CA_HUMAN	KS6B1_HUMAN	kinase -> substrate	HPRD
19	BTK_HUMAN	ITK_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
20	BTK_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
21	BTK_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
22	BTK_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
23	BTK_HUMAN	CDK9_HUMAN	kinase -> substrate	Robert H Newman (2013)
24	KPCD1_HUMAN	KSYK_HUMAN	kinase -> substrate	NetPath
25	MK01_HUMAN	MYC_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
26	MK01_HUMAN	SP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
27	MK01_HUMAN	SOS1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
28	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
29	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
30	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
31	MK01_HUMAN	ELK1_HUMAN	kinase -> substrate	NetPath
32	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
33	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
34	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
35	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
36	MK01_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD
37	STA5A_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
38	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
39	MK01_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
40	MK01_HUMAN	MITF_HUMAN	kinase -> substrate	NetPath
41	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
42	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
43	KS6A2_HUMAN	FOS_HUMAN	kinase -> substrate	RegPhos
44	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
45	KS6A2_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
46	MK01_HUMAN	RXRA_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
47	KS6B1_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
48	MK01_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
49	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
50	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
51	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
52	P53_HUMAN	ATF3_HUMAN	TF -> target gene	TRANSFAC
53	MK01_HUMAN	TFE2_HUMAN	kinase -> substrate	HPRD; NetPath
54	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
55	KS6A2_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
56	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
57	MK01_HUMAN	PRGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
58	ITK_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
59	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
60	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	MK01_HUMAN	PPARA_HUMAN	kinase -> substrate	HPRD
62	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
63	MK01_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
64	KS6A2_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
65	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
66	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
67	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
68	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
69	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
70	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
71	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
72	SMAD3_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
73	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
74	MK01_HUMAN	ELK4_HUMAN	kinase -> substrate	KEGG
75	KS6A2_HUMAN	CEBPB_HUMAN	kinase -> substrate	RegPhos
76	MK01_HUMAN	STF1_HUMAN	kinase -> substrate	HPRD
77	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
78	P53_HUMAN	P73_HUMAN	TF -> target gene	KEGG; TRANSFAC
79	MK01_HUMAN	STK16_HUMAN	kinase -> substrate	Robert H Newman (2013)
80	KS6B1_HUMAN	MTOR_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
81	KS6A2_HUMAN	SRF_HUMAN	kinase -> substrate	RegPhos
82	MK01_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
83	KS6A2_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
84	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
85	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
86	CDK9_HUMAN	CHK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
87	KS6B1_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
88	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
89	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
90	MK01_HUMAN	SMAD4_HUMAN	kinase -> substrate	HPRD
91	KS6B1_HUMAN	HSF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
92	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
93	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
94	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
95	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
96	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
97	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
98	KSYK_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
99	MK01_HUMAN	CEBPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
100	KS6B1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
101	KS6A2_HUMAN	NR4A1_HUMAN	kinase -> substrate	RegPhos
102	MK01_HUMAN	JUN_HUMAN	kinase -> substrate	KEGG
103	MK01_HUMAN	THB_HUMAN	kinase -> substrate	Robert H Newman (2013)
104	MK01_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD
105	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
106	MK01_HUMAN	PKN1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
107	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
108	MK01_HUMAN	CEBPB_HUMAN	kinase -> substrate	HPRD
109	MK01_HUMAN	SRBP2_HUMAN	kinase -> substrate	Robert H Newman (2013)
110	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
111	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
112	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
113	MK01_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD
114	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
115	MK01_HUMAN	MP2K1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
116	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
117	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
118	MK01_HUMAN	BCL6_HUMAN	kinase -> substrate	NetPath
119	KS6A2_HUMAN	KS6A1_HUMAN	kinase -> substrate	RegPhos
120	MK01_HUMAN	MYB_HUMAN	kinase -> substrate	HPRD
121	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
122	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
123	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	KSYK_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
125	MK01_HUMAN	GSK3B_HUMAN	kinase -> substrate	Robert H Newman (2013)
126	MK01_HUMAN	FOS_HUMAN	kinase -> substrate; other	KEGG
127	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
128	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
129	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
130	MK01_HUMAN	SRBP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
131	KSYK_HUMAN	KS6A1_HUMAN	kinase -> substrate	NetPath
132	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
133	SP1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
134	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
135	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
136	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
137	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
138	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
139	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
140	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
141	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
142	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
143	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
144	SP1_HUMAN	CDK2_HUMAN	TF -> target gene	TRANSFAC
145	SP1_HUMAN	AP2C_HUMAN	TF -> target gene	TRANSFAC
146	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
147	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
148	SP1_HUMAN	RARA_HUMAN	TF -> target gene	TRANSFAC
149	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
150	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
151	STK16_HUMAN	IRF5_HUMAN	kinase -> substrate	Robert H Newman (2013)
152	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
153	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
154	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
155	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
156	CHK2_HUMAN	E2F1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
157	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
158	SP1_HUMAN	MAZ_HUMAN	TF -> target gene	TRANSFAC
159	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
160	SP1_HUMAN	SP3_HUMAN	TF -> target gene	TRANSFAC
161	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
162	SP1_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
163	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
164	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
165	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
166	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
167	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
168	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
169	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
170	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
171	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
172	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
173	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
174	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
175	SP1_HUMAN	HNF4A_HUMAN	TF -> target gene	TRANSFAC
176	SP1_HUMAN	TGFR2_HUMAN	TF -> target gene	TRANSFAC
177	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
178	SP1_HUMAN	PHX2A_HUMAN	TF -> target gene	TRANSFAC
179	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
180	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
181	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
182	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
183	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
184	CDK2_HUMAN	NFYA_HUMAN	kinase -> substrate	HPRD
185	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
186	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
187	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
188	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
189	CDK2_HUMAN	TFDP1_HUMAN	kinase -> substrate	RegPhos
190	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
191	TGFR2_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
192	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
193	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network