Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GNA11_HUMAN
Description:guanine nucleotide binding protein (G protein), alpha 11 (Gq class) [Source:HGNC Symbol;Acc:4379]
Location:chr19 p13.3
Node attribute:PPI(source); Gprotein; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S50LGTGEsGKSTFG-alphaPhosphoSitePlus
T169VDRIAtLGYLPG-alphaPhosphoSitePlus
Y80FTKLVyQNIFTG-alphaPhosphoSitePlus
T162AKYYLtDVDRIHPRD
S154REYQLsDSAKYG-alphaPhosphoSitePlus

Dephosphorylation site
GNA11_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000078429R256WCOSMICMelanoma
ENSP00000078429V223MCOSMICMelanoma20424519
ENSP00000078429Y235*COSMICOvarian Cancer21720365
ENSP00000078429N266KCOSMICMelanoma20424519
ENSP00000078429R183CCOSMICMelanoma
ENSP00000078429D333YCOSMICMelanoma20424519
ENSP00000078429Q209LCOSMICHead and Neck Cancer21874003

Differential expressed protein
GNA11_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GNA11_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CASR_HUMANGNA11_HUMANGPCR -> GproteingpDB
MCHR2_HUMANGNA11_HUMANGPCR -> GproteingpDB
PRLHR_HUMANGNA11_HUMANGPCR -> GproteingpDB
LSHR_HUMANGNA11_HUMANGPCR -> GproteingpDB
PAR4_HUMANGNA11_HUMANGPCR -> GproteingpDB
CLTR2_HUMANGNA11_HUMANGPCR -> GproteingpDB
P2RY2_HUMANGNA11_HUMANGPCR -> GproteingpDB
FZD2_HUMANGNA11_HUMANGPCR -> GproteingpDB
5HT2B_HUMANGNA11_HUMANGPCR -> GproteingpDB
NK3R_HUMANGNA11_HUMANGPCR -> GproteingpDB
AGTR1_HUMANGNA11_HUMANGPCR -> GproteingpDB
PF2R_HUMANGNA11_HUMANGPCR -> GproteingpDB
ADA2A_HUMANGNA11_HUMANGPCR -> GproteingpDB
P2Y11_HUMANGNA11_HUMANGPCR -> GproteingpDB
FZD1_HUMANGNA11_HUMANGPCR -> GproteingpDB
ACM3_HUMANGNA11_HUMANGPCR -> GproteingpDB
P2RY4_HUMANGNA11_HUMANGPCR -> GproteingpDB
V1BR_HUMANGNA11_HUMANGPCR -> GproteingpDB
SUCR1_HUMANGNA11_HUMANGPCR -> GproteingpDB
S1PR2_HUMANGNA11_HUMANGPCR -> GproteingpDB
OXYR_HUMANGNA11_HUMANGPCR -> GproteingpDB
GNRR2_HUMANGNA11_HUMANGPCR -> GproteingpDB
PAR3_HUMANGNA11_HUMANGPCR -> GproteingpDB
LPAR4_HUMANGNA11_HUMANGPCR -> GproteingpDB
NMUR2_HUMANGNA11_HUMANGPCR -> GproteingpDB
MCHR1_HUMANGNA11_HUMANGPCR -> GproteingpDB
GRM1_HUMANGNA11_HUMANGPCR -> GproteingpDB
PTAFR_HUMANGNA11_HUMANGPCR -> GproteingpDB
LPAR1_HUMANGNA11_HUMANGPCR -> GproteingpDB
LT4R2_HUMANGNA11_HUMANGPCR -> GproteingpDB
P2RY6_HUMANGNA11_HUMANGPCR -> GproteingpDB
S1PR3_HUMANGNA11_HUMANGPCR -> GproteingpDB
LT4R1_HUMANGNA11_HUMANGPCR -> GproteingpDB
ADA1A_HUMANGNA11_HUMANGPCR -> GproteingpDB
GHSR_HUMANGNA11_HUMANGPCR -> GproteingpDB
ADA1D_HUMANGNA11_HUMANGPCR -> GproteingpDB
CALCR_HUMANGNA11_HUMANGPCR -> GproteingpDB
PAR1_HUMANGNA11_HUMANGPCR -> GproteingpDB
PE2R3_HUMANGNA11_HUMANGPCR -> GproteingpDB
EDNRB_HUMANGNA11_HUMANGPCR -> GproteingpDB
CLTR1_HUMANGNA11_HUMANGPCR -> GproteingpDB
LPAR2_HUMANGNA11_HUMANGPCR -> GproteingpDB
EDNRA_HUMANGNA11_HUMANGPCR -> GproteingpDB
NK2R_HUMANGNA11_HUMANGPCR -> GproteingpDB
5HT2C_HUMANGNA11_HUMANGPCR -> GproteingpDB
GALR2_HUMANGNA11_HUMANGPCR -> GproteingpDB
ACM5_HUMANGNA11_HUMANGPCR -> GproteingpDB
BKRB1_HUMANGNA11_HUMANGPCR -> GproteingpDB
NTR2_HUMANGNA11_HUMANGPCR -> GproteingpDB
TRFR_HUMANGNA11_HUMANGPCR -> GproteingpDB
5HT2A_HUMANGNA11_HUMANGPCR -> GproteingpDB
PAR2_HUMANGNA11_HUMANGPCR -> GproteingpDB
NTR1_HUMANGNA11_HUMANGPCR -> GproteingpDB
LPAR3_HUMANGNA11_HUMANGPCR -> GproteingpDB
TA2R_HUMANGNA11_HUMANGPCR -> GproteingpDB
GNRHR_HUMANGNA11_HUMANGPCR -> GproteingpDB
PE2R1_HUMANGNA11_HUMANGPCR -> GproteingpDB
GNA11_HUMANPLCB1_HUMANGprotein -> effectorgpDB
GNA11_HUMANARBK2_HUMANGprotein -> effectorgpDB
GNA11_HUMANPLCB3_HUMANGprotein -> effectorgpDB
GNA11_HUMANPLCB4_HUMANGprotein -> effectorgpDB
GNA11_HUMANPLCB2_HUMANGprotein -> effectorgpDB
GNA11_HUMANARBK1_HUMANGprotein -> effectorgpDB
GNA11_HUMANGRK4_HUMANGprotein -> effectorgpDB
GNA11_HUMANPLCB1_HUMANotherKEGG
GNRHR_HUMANGNA11_HUMANotherKEGG
CLTR1_HUMANGNA11_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04725Cholinergic synapse
hsa05146Amoebiasis
hsa04270Vascular smooth muscle contraction
hsa04912GnRH signaling pathway
hsa04730Long-term depression
hsa04540Gap junction
hsa05142Chagas disease (American trypanosomiasis)
hsa04020Calcium signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001664G-protein coupled receptor bindingIBAmolecular_function
GO:0048066developmental pigmentationIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0005525GTP bindingIEAmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007507heart developmentIEAbiological_process
GO:0060158phospholipase C-activating dopamine receptor signaIEAbiological_process
GO:0060158phospholipase C-activating dopamine receptor signaIBAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0001501skeletal system developmentIEAbiological_process
GO:0005834heterotrimeric G-protein complexIBAcellular_component
GO:0031234extrinsic to internal side of plasma membraneIBAcellular_component
GO:0007188adenylate cyclase-modulating G-protein coupled recIBAbiological_process
GO:0019001guanyl nucleotide bindingIEAmolecular_function
GO:0005737cytoplasmTAScellular_component
GO:0001508regulation of action potentialIBAbiological_process
GO:0001508regulation of action potentialIEAbiological_process
GO:0004871signal transducer activityIBAmolecular_function
GO:0006184GTP catabolic processTASbiological_process
GO:0031683G-protein beta/gamma-subunit complex bindingIBAmolecular_function
GO:0045634regulation of melanocyte differentiationIEAbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0030168platelet activationTASbiological_process
GO:0007165signal transductionTASbiological_process
GO:0006471protein ADP-ribosylationIEAbiological_process
GO:0003924GTPase activityTASmolecular_function


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