Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NTKL_HUMAN
Description:SCY1-like 1 (S. cerevisiae) [Source:HGNC Symbol;Acc:14372]
Location:chr11 q13.1
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S638DTAEDsSTADRPhosphoSitePlus
S681SQVSNsDHKSSPhosphoSitePlus; HPRD
S664SQVSNsDHKSSHPRD
Y725RLASEyNWGGPPhosphoSitePlus
T741GDPFAtLSARPPhosphoSitePlus
S558DVHAAsSPGMGHPRD; SysPTM
T634EEDKDtAEDSSPhosphoSitePlus
S747LSARPsTQPRPPhosphoSitePlus
T640AEDSStADRWDPhosphoSitePlus
S639TAEDSsTADRWPhosphoSitePlus
S754QPRPDsWGEDNPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T332GAVVLtPLFKVPhosphoSitePlus
S737QPRPDsWGEDNHPRD
S568GGAAAsWAGWAPhosphoSitePlus; HPRD

Dephosphorylation site
NTKL_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000270176H495QCOSMICOvarian Cancer21720365
ENSP00000408192E673GTCGAOvarian Cancer21720365, 18772890
ENSP00000408192H495QTCGAOvarian Cancer21720365, 18772890
ENSP00000270176E690GCOSMICOvarian Cancer21720365
ENSP00000270176H495YGreenman2007Skin Cancer17344846, 18428421

Differential expressed protein
NTKL_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NTKL_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NTKL_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
NTKL_HUMANDGCR8_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
NTKL_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0004713protein tyrosine kinase activityNASmolecular_function
GO:0005815microtubule organizing centerIEAcellular_component
GO:0004672protein kinase activityIEAmolecular_function
GO:0005488bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005793endoplasmic reticulum-Golgi intermediate compartmeIDAcellular_component
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0030126COPI vesicle coatIEAcellular_component
GO:0006468protein phosphorylationIEAbiological_process
GO:0030126COPI vesicle coatIDAcellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005737cytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006890retrograde vesicle-mediated transport, Golgi to ERIDAbiological_process
GO:0005801cis-Golgi networkIDAcellular_component
GO:0005737cytoplasmIEAcellular_component


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