| UniProt/SwissProt ID: | TSAP1_HUMAN |
| Description: | tRNA selenocysteine 1 associated protein 1 [Source:HGNC Symbol;Acc:30813] |
| Location: | chr1 p35.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T74 | PLPGAtPAKRF | RRM_1 | PhosphoSitePlus |
| S32 | GETVMsVKIIR | RRM_1 | PhosphoSitePlus |
| Dephosphorylation site |
| TSAP1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000362936 | S192T | COSMIC | Ovarian Cancer | 21720365 | ENSP00000362936 | S192T | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| TSAP1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TSAP1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| BMX_HUMAN | TSAP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TSAP1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0001514 | selenocysteine incorporation | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005634 | nucleus | ISS | cellular_component |
| GO:0000166 | nucleotide binding | IEA | molecular_function |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0001514 | selenocysteine incorporation | ISS | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003723 | RNA binding | IEA | molecular_function |