| UniProt/SwissProt ID: | STAR3_HUMAN |
| Description: | StAR-related lipid transfer (START) domain containing 3 [Source:HGNC Symbol;Acc:17579] |
| Location: | chr17 q12 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S146 | LSELLsKGAFG | PhosphoSitePlus | |
| S209 | EGQFYsPPESF | PhosphoSitePlus; HPRD | |
| S221 | GSDNEsDEEVA | PhosphoSitePlus; HPRD | |
| S217 | ESFAGsDNESD | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| STAR3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000337446 | E429Q | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000377794 | E411Q | BIOMART | Pancreatic Cancer | 21930507, 21930502 |
| Differential expressed protein |
| STAR3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| STAR3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| BMX_HUMAN | STAR3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| STAR3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006701 | progesterone biosynthetic process | IEA | biological_process |
| GO:0005737 | cytoplasm | TAS | cellular_component |
| GO:0008202 | steroid metabolic process | TAS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0015485 | cholesterol binding | IDA | molecular_function |
| GO:0006839 | mitochondrial transport | TAS | biological_process |
| GO:0031902 | late endosome membrane | IEA | cellular_component |
| GO:0017127 | cholesterol transporter activity | IEA | molecular_function |
| GO:0006629 | lipid metabolic process | TAS | biological_process |
| GO:0008203 | cholesterol metabolic process | TAS | biological_process |