Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GLHA_HUMAN
Description:glycoprotein hormones, alpha polypeptide [Source:HGNC Symbol;Acc:1885]
Location:chr6 q14.3
Node attribute:PPI(source); ligand; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T63SRAYPtPLRSKHormone_6PhosphoSitePlus
T63SRAYPtPLRSKphosphoELM

Dephosphorylation site
GLHA_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000358595R91MBIOMARTBreast Cancer21930507, 21930502
ENSP00000358595G96ACOSMICOvarian Cancer21720365

Differential expressed protein
GLHA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GLHA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GLHA_HUMANLSHR_HUMANligand -> receptorHPMR
GLHA_HUMANTRFR_HUMANotherKEGG
GLHA_HUMANMAS_HUMANotherKEGG
GLHA_HUMANRXFP2_HUMANotherKEGG
GLHA_HUMANPACR_HUMANotherKEGG
GLHA_HUMANCALRL_HUMANotherKEGG
GLHA_HUMANPF2R_HUMANotherKEGG
GLHA_HUMANGIPR_HUMANotherKEGG
GLHA_HUMANNMD3A_HUMANotherKEGG
GLHA_HUMANGBRR3_HUMANotherKEGG
GLHA_HUMANGLRA1_HUMANotherKEGG
GLHA_HUMANPI2R_HUMANotherKEGG
GLHA_HUMANTA2R_HUMANotherKEGG
GLHA_HUMANCRFR1_HUMANotherKEGG
GLHA_HUMANP2RX2_HUMANotherKEGG
GLHA_HUMANCNR1_HUMANotherKEGG
GLHA_HUMANFSHR_HUMANotherKEGG
GLHA_HUMANPD2R_HUMANotherKEGG
GLHA_HUMANLSHR_HUMANotherKEGG
GLHA_HUMANGP156_HUMANotherKEGG
GLHA_HUMANGCR_HUMANotherKEGG
GLHA_HUMANGNRHR_HUMANotherKEGG
GLHA_HUMANTRPV1_HUMANotherKEGG
GLHA_HUMANTSPOB_HUMANotherKEGG
GLHA_HUMANGLP1R_HUMANotherKEGG
GLHA_HUMANLPAR6_HUMANotherKEGG
GLHA_HUMANCLTR1_HUMANotherKEGG
GLHA_HUMANSCTR_HUMANotherKEGG
GLHA_HUMANMTR1A_HUMANotherKEGG
GLHA_HUMANAA1R_HUMANotherKEGG
GLHA_HUMANPE2R1_HUMANotherKEGG
GLHA_HUMANTSHR_HUMANotherKEGG
GLHA_HUMANPTH1R_HUMANotherKEGG
GLHA_HUMANGRM1_HUMANotherKEGG
GLHA_HUMANGHRHR_HUMANotherKEGG
GLHA_HUMANVIPR1_HUMANotherKEGG
GLHA_HUMANGLR_HUMANotherKEGG
GLHA_HUMANS1PR1_HUMANotherKEGG
GLHA_HUMANLT4R1_HUMANotherKEGG
THB_HUMANGLHA_HUMANTF -> target geneTRANSFAC
CREB1_HUMANGLHA_HUMANTF -> target geneTRANSFAC
GCR_HUMANGLHA_HUMANTF -> target geneTRANSFAC
ATF2_HUMANGLHA_HUMANTF -> target geneTRANSFAC
NFIC_HUMANGLHA_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction
hsa05320Autoimmune thyroid disease
hsa04912GnRH signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016486peptide hormone processingTASbiological_process
GO:0007267cell-cell signalingTASbiological_process
GO:0008406gonad developmentIEAbiological_process
GO:0008284positive regulation of cell proliferationNASbiological_process
GO:0046884follicle-stimulating hormone secretionIEAbiological_process
GO:0006590thyroid hormone generationIEAbiological_process
GO:0030335positive regulation of cell migrationNASbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0034641cellular nitrogen compound metabolic processTASbiological_process
GO:0032870cellular response to hormone stimulusIEAbiological_process
GO:0005179hormone activityIEAmolecular_function
GO:0007165signal transductionTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0030878thyroid gland developmentIEAbiological_process
GO:0032275luteinizing hormone secretionIEAbiological_process
GO:0048589developmental growthIEAbiological_process
GO:0046621negative regulation of organ growthIEAbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0045944positive regulation of transcription from RNA polyNASbiological_process


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