Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GLRA1_HUMAN
Description:glycine receptor, alpha 1 [Source:HGNC Symbol;Acc:4326]
Location:chr5 q33.1
Node attribute:PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S419KIDKIsRIGFPHPRD
Y307LPKVSyVKAIDNeur_chan_membPhosphoSitePlus
Y52GRTSGyDARIRNeur_chan_LBDPhosphoSitePlus
S324LLFVFsALLEYNeur_chan_memb; TMPhosphoSitePlus

Dephosphorylation site
GLRA1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000411593A29PBIOMARTBreast Cancer21930507, 21930502
ENSP00000274576A203SCOSMICOvarian Cancer21720365
ENSP00000274576A29PBIOMARTBreast Cancer21930507, 21930502
ENSP00000274576R159KCOSMICSkin Cancer21984974
ENSP00000274576R246WCOSMICCentral Nervous System Neoplasms18772396
ENSP00000274576T391ICOSMICSkin Cancer21984974

Differential expressed protein
GLRA1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GLRA1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GLHA_HUMANGLRA1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:2000344positive regulation of acrosome reactionIMPbiological_process
GO:0016934extracellular-glycine-gated chloride channel activIEAmolecular_function
GO:0030977taurine bindingIDAmolecular_function
GO:0043576regulation of respiratory gaseous exchangeIEAbiological_process
GO:0005887integral to plasma membraneIEAcellular_component
GO:0005622intracellularIEAcellular_component
GO:0042391regulation of membrane potentialIMPbiological_process
GO:0001508regulation of action potentialIEAbiological_process
GO:0016594glycine bindingIEAmolecular_function
GO:0045211postsynaptic membraneIEAcellular_component
GO:0055085transmembrane transportTASbiological_process
GO:0002087regulation of respiratory gaseous exchange by neurIEAbiological_process
GO:0042391regulation of membrane potentialIEAbiological_process
GO:0007628adult walking behaviorIEAbiological_process
GO:0022824transmitter-gated ion channel activityIEAmolecular_function
GO:0030054cell junctionIEAcellular_component
GO:0016933extracellular-glycine-gated ion channel activityIEAmolecular_function
GO:0050884neuromuscular process controlling postureIEAbiological_process
GO:0009897external side of plasma membraneIEAcellular_component
GO:0006810transportIEAbiological_process
GO:0005783endoplasmic reticulumIEAcellular_component
GO:0006821chloride transportIEAbiological_process
GO:0034707chloride channel complexIEAcellular_component
GO:0007218neuropeptide signaling pathwayIDAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0060080regulation of inhibitory postsynaptic membrane potIEAbiological_process
GO:0006820anion transportIEAbiological_process
GO:0050905neuromuscular processIEAbiological_process
GO:0016021integral to membraneNAScellular_component
GO:0005887integral to plasma membraneIMPcellular_component
GO:0001964startle responseIEAbiological_process
GO:0060013righting reflexIEAbiological_process
GO:0007268synaptic transmissionIEAbiological_process
GO:0051970negative regulation of transmission of nerve impulIMPbiological_process
GO:0016594glycine bindingIDAmolecular_function
GO:0007601visual perceptionIEAbiological_process
GO:0006936muscle contractionIMPbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0006811ion transportIDAbiological_process
GO:0005230extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0034220ion transmembrane transportTASbiological_process
GO:0051260protein homooligomerizationIEAbiological_process
GO:0060012synaptic transmission, glycinergicIEAbiological_process
GO:0043231intracellular membrane-bounded organelleIDAcellular_component
GO:0016020membraneIEAcellular_component
GO:0007340acrosome reactionIEAbiological_process
GO:0001964startle responseIMPbiological_process
GO:0016934extracellular-glycine-gated chloride channel activIGImolecular_function
GO:0006821chloride transportIDAbiological_process
GO:0051291protein heterooligomerizationIEAbiological_process


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