Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MAS_HUMAN
Description:MAS1 oncogene [Source:HGNC Symbol;Acc:6899]
Location:chr6 q25.3
Node attribute:receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y121YNTGLyLLTAI7tm_1; TMPhosphoSitePlus

Dephosphorylation site
MAS_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000252660L120FCOSMICLung Cancer20668451
ENSP00000252660G20CCOSMICOvarian Cancer21720365
ENSP00000252660V152ACOSMICLung Cancer20668451
ENSP00000252660R144HBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000252660V198FCOSMICHead and Neck Cancer21798893
ENSP00000252660T118MCOSMICOvarian Cancer20826764

Differential expressed protein
MAS_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MAS_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ANGT_HUMANMAS_HUMANligand -> receptorHPMR
GLHA_HUMANMAS_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction
hsa04614Renin-angiotensin system

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0038166angiotensin-mediated signaling pathwayIEAbiological_process
GO:0071375cellular response to peptide hormone stimulusIEAbiological_process
GO:0004930G-protein coupled receptor activityIDAmolecular_function
GO:0007283spermatogenesisIEAbiological_process
GO:0042277peptide bindingIEAmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0060732positive regulation of inositol phosphate biosynthIEAbiological_process
GO:0009653anatomical structure morphogenesisTASbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0045740positive regulation of DNA replicationIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0004945angiotensin type II receptor activityTASmolecular_function
GO:0007250activation of NF-kappaB-inducing kinase activityIEAbiological_process
GO:0021766hippocampus developmentIEAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0001595angiotensin receptor activityIEAmolecular_function
GO:0001933negative regulation of protein phosphorylationIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0001595angiotensin receptor activityISSmolecular_function
GO:0008584male gonad developmentIEAbiological_process
GO:0034698response to gonadotropin stimulusIEAbiological_process
GO:0017046peptide hormone bindingIEAmolecular_function
GO:0008283cell proliferationTASbiological_process
GO:0070528protein kinase C signaling cascadeIMPbiological_process
GO:0009986cell surfaceIEAcellular_component
GO:0050727regulation of inflammatory responseIEAbiological_process
GO:0043434response to peptide hormone stimulusIEAbiological_process
GO:0014823response to activityIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0042277peptide bindingISSmolecular_function


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