Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GLP1R_HUMAN
Description:glucagon-like peptide 1 receptor [Source:HGNC Symbol;Acc:4324]
Location:chr6 p21.2
Node attribute:GPCR; receptor; PPI(target)

Phosphorylation site
GLP1R_HUMAN do not have phosphorylation site.

Dephosphorylation site
GLP1R_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000362353E68GBIOMARTBreast Cancer21930507, 21930502
ENSP00000362353Q428RCOSMICBreast Cancer20668451
ENSP00000362353S432RCOSMICLung Cancer
ENSP00000362353A399DCOSMICLung Cancer20668451
ENSP00000362353V325LBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
GLP1R_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GLP1R_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GLUC_HUMANGLP1R_HUMANligand -> receptorHPMR
GLP1R_HUMANGNAS1_HUMANGPCR -> GproteingpDB
GLP1R_HUMANGNAS2_HUMANGPCR -> GproteingpDB
GLHA_HUMANGLP1R_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0050796regulation of insulin secretionTASbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0008528G-protein coupled peptide receptor activityIEAmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007204elevation of cytosolic calcium ion concentrationIDAbiological_process
GO:0007190activation of adenylate cyclase activityTASbiological_process
GO:0007166cell surface receptor signaling pathwayIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0004967glucagon receptor activityIEAmolecular_function
GO:0006112energy reserve metabolic processTASbiological_process
GO:0004888transmembrane signaling receptor activityTASmolecular_function
GO:0019933cAMP-mediated signalingIDAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0044281small molecule metabolic processTASbiological_process


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