Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:P2RX2_HUMAN
Description:purinergic receptor P2X, ligand-gated ion channel, 2 [Source:HGNC Symbol;Acc:15459]
Location:chr12 q24.33
Node attribute:PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y307RFAKYyKINGTP2X_receptorPhosphoSitePlus
Y222DRTDGyLKRCTP2X_receptorPhosphoSitePlus
Y306FRFAKyYKINGP2X_receptorPhosphoSitePlus
Y299PASSGyNFRFAP2X_receptorPhosphoSitePlus
T312YKINGtTTRTLP2X_receptorPhosphoSitePlus

Dephosphorylation site
P2RX2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000343339Q380EBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
P2RX2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
P2RX2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GLHA_HUMANP2RX2_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction
hsa04020Calcium signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051260protein homooligomerizationIPIbiological_process
GO:0050909sensory perception of tasteIEAbiological_process
GO:0045340mercury ion bindingIEAmolecular_function
GO:0004931extracellular ATP-gated cation channel activityIBAmolecular_function
GO:0043195terminal buttonIEAcellular_component
GO:0008144drug bindingIEAmolecular_function
GO:0016151nickel cation bindingIEAmolecular_function
GO:0015276ligand-gated ion channel activityTASmolecular_function
GO:0015276ligand-gated ion channel activityIEAmolecular_function
GO:0035590purinergic nucleotide receptor signaling pathwayIBAbiological_process
GO:0003029detection of hypoxic conditions in blood by carotiIEAbiological_process
GO:0004931extracellular ATP-gated cation channel activityIEAmolecular_function
GO:0033198response to ATPIEAbiological_process
GO:0050850positive regulation of calcium-mediated signalingNASbiological_process
GO:0007274neuromuscular synaptic transmissionIEAbiological_process
GO:0046870cadmium ion bindingIEAmolecular_function
GO:0001666response to hypoxiaIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0010033response to organic substanceIEAbiological_process
GO:0007268synaptic transmissionIEAbiological_process
GO:0007528neuromuscular junction developmentIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0043025neuronal cell bodyIEAcellular_component
GO:0051291protein heterooligomerizationIEAbiological_process
GO:0009743response to carbohydrate stimulusIEAbiological_process
GO:0005524ATP bindingNASmolecular_function
GO:0042734presynaptic membraneIEAcellular_component
GO:0048266behavioral response to painIEAbiological_process
GO:0014069postsynaptic densityIEAcellular_component
GO:0006812cation transportIBAbiological_process
GO:0043197dendritic spineIEAcellular_component
GO:0005507copper ion bindingIEAmolecular_function
GO:0006811ion transportIEAbiological_process
GO:0050897cobalt ion bindingIEAmolecular_function
GO:0008270zinc ion bindingIEAmolecular_function
GO:0030432peristalsisIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0042802identical protein bindingIPImolecular_function
GO:0010524positive regulation of calcium ion transport into NASbiological_process
GO:0044424intracellular partIEAcellular_component
GO:0019228regulation of action potential in neuronIEAbiological_process
GO:0016020membraneIBAcellular_component
GO:0014832urinary bladder smooth muscle contractionIEAbiological_process
GO:0035091phosphatidylinositol bindingIEAmolecular_function
GO:0005216ion channel activityIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0001614purinergic nucleotide receptor activityIBAmolecular_function
GO:0048741skeletal muscle fiber developmentIEAbiological_process


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