| UniProt/SwissProt ID: | TSHR_HUMAN |
| Description: | thyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:12373] |
| Location: | chr14 q31.1 |
| Node attribute: | PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S298 | RGILEsLMCNE | PhosphoSitePlus | |
| Y739 | NMEDVyELIEN | PhosphoSitePlus | |
| S745 | ELIENsHLTPK | PhosphoSitePlus | |
| T748 | ENSHLtPKKQG | PhosphoSitePlus | |
| Y706 | RQAQAyRGQRV | PhosphoSitePlus | |
| S268 | LPLSLsFLHLT | PhosphoSitePlus | |
| S308 | ESSMQsLRQRK | PhosphoSitePlus | |
| S425 | VVWFVsLLALL | TM | PhosphoSitePlus |
| Y225 | AFGGVySGPSL | PhosphoSitePlus | |
| Dephosphorylation site |
| TSHR_HUMAN do not have dephosphorylation site. |
| Mutation site |
| TSHR_HUMAN do not have mutation site. |
| Differential expressed protein |
| TSHR_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TSHR_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GLHA_HUMAN | TSHR_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa05320 | Autoimmune thyroid disease |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0040012 | regulation of locomotion | IEA | biological_process |
| GO:0007187 | G-protein coupled receptor signaling pathway, coup | TAS | biological_process |
| GO:0040018 | positive regulation of multicellular organism grow | IEA | biological_process |
| GO:0008284 | positive regulation of cell proliferation | TAS | biological_process |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0008344 | adult locomotory behavior | IEA | biological_process |
| GO:0007267 | cell-cell signaling | TAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007189 | adenylate cyclase-activating G-protein coupled rec | IEA | biological_process |
| GO:0030183 | B cell differentiation | IEA | biological_process |
| GO:0004996 | thyroid-stimulating hormone receptor activity | IEA | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |