Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:AURKB_HUMAN
Description:aurora kinase B [Source:HGNC Symbol;Acc:11390]
Location:chr17 p13.1
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T232SLRRKtMCGTLAurora BphosphoELM; SysPTM
T232SLRRKtMCGTLHPRD; phosphoELM; RegPhos; SysPTM
T64ENSSGtPDILTPhosphoSitePlus; HPRD; SysPTM
S227SVHAPsLRRKTPkinasePhosphoSitePlus; SysPTM
S331WVRANsRRVLPPhosphoSitePlus
Y12SYPWPyGRQTAPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T236KTMCGtLDYLPPkinasePhosphoSitePlus; SysPTM
Y8QKENSyPWPYGPhosphoSitePlus
T16PYGRQtAPSGLHPRD
S313LRHNPsERLPLHPRD; SysPTM
S313LRHNPsERLPLPkinasePhosphoSitePlus; SysPTM
T236KTMCGtLDYLPHPRD; phosphoELM; SysPTM
Y92KFGNVyLAREKPkinasePhosphoSitePlus; SysPTM
Y92KFGNVyLAREKHPRD; SysPTM
S7PWPYHPRD; phosphoELM; SysPTM
S227SVHAPsLRRKTHPRD; SysPTM
S62VMENSsGTPDIPhosphoSitePlus; HPRD
T232SLRRKtMCGTLAurB(Aurora BRegPhos; SysPTM
S45VLMSRsNVQPTPhosphoSitePlus; HPRD; SysPTM
T232SLRRKtMCGTLPkinasePhosphoSitePlus; SysPTM
S61KVMENsSGTPDPhosphoSitePlus; HPRD; SysPTM
T73LTRHFtIDDFEPhosphoSitePlus
S7AQKENsYPWPYPhosphoSitePlus; RegPhos; SysPTM
T35RKEPVtPSALVPhosphoSitePlus; HPRD; phosphoELM; SysPTM

Dephosphorylation site
AURKB_HUMAN do not have dephosphorylation site.

Mutation site
AURKB_HUMAN do not have mutation site.

Differential expressed protein
AURKB_HUMAN is not differential expressed protein.

Hyperphosphorylation site
AURKB_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
AURKB_HUMANMBNL3_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANKKCC1_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANHCLS1_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANMTA1_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANCENPA_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
AURKB_HUMANNOL7_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANOTU7B_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANRFA1_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANINCE_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
AURKB_HUMANIASPP_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANZIC4_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANDESM_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
AURKB_HUMANCHK2_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANH33_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANMDM4_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANMDFI_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANSRC8_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANGFAP_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANSOX10_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANPKNX1_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANFEV_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANKPCA_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANNSUN2_HUMANkinase -> substrateHPRD
AURKB_HUMANZBED1_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANSEPT1_HUMANkinase -> substrateHPRD
ZAGL2_HUMANAURKB_HUMANkinase -> substrateRegPhos
AURKB_HUMANVIME_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANMRF_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANZN606_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANCNOT6_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANKIF2C_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANRGAP1_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
AURKB_HUMANM18BP_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANZYX_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANHSFX1_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANPRDM1_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANXRCC1_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANH31_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANGIT2_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANCBL_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANPRS6A_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANBIRC5_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANDAPK2_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANPER1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
AURKB_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0002903negative regulation of B cell apoptotic processIDAbiological_process
GO:0004712protein serine/threonine/tyrosine kinase activityTASmolecular_function
GO:0034501protein localization to kinetochoreIMPbiological_process
GO:0007049cell cycleIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIDAbiological_process
GO:0036089cleavage furrow formationIDAbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0000278mitotic cell cycleTASbiological_process
GO:0000779condensed chromosome, centromeric regionIDAcellular_component
GO:0005829cytosolTAScellular_component
GO:0032133chromosome passenger complexIPIcellular_component
GO:0000910cytokinesisIEAbiological_process
GO:0034644cellular response to UVIDAbiological_process
GO:0000780condensed nuclear chromosome, centromeric regionIDAcellular_component
GO:0071777positive regulation of cell cycle cytokinesisIMPbiological_process
GO:0046777protein autophosphorylationTASbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0008608attachment of spindle microtubules to kinetochoreTASbiological_process
GO:0008283cell proliferationIEAbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0030496midbodyIEAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0000236mitotic prometaphaseTASbiological_process
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0016570histone modificationTASbiological_process
GO:0007568agingIEAbiological_process
GO:0051983regulation of chromosome segregationTASbiological_process
GO:0005819spindleIEAcellular_component
GO:0032133chromosome passenger complexIEAcellular_component
GO:0010369chromocenterIEAcellular_component
GO:0005819spindleTAScellular_component
GO:0000087M phase of mitotic cell cycleTASbiological_process
GO:0030496midbodyTAScellular_component
GO:0004672protein kinase activityIEAmolecular_function
GO:0031145anaphase-promoting complex-dependent proteasomal uTASbiological_process
GO:0051256spindle midzone assembly involved in mitosisIMPbiological_process


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