| UniProt/SwissProt ID: | FEV_HUMAN |
| Description: | FEV (ETS oncogene family) [Source:HGNC Symbol;Acc:18562] |
| Location: | chr2 q35 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y98 | KPNMNyDKLSR | Ets | PhosphoSitePlus |
| Dephosphorylation site |
| FEV_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000295727 | D99H | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| FEV_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| FEV_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CLK2_HUMAN | FEV_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| AURKB_HUMAN | FEV_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| DDR1_HUMAN | FEV_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| VRK3_HUMAN | FEV_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| FEV_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006366 | transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0048665 | neuron fate specification | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IEA | biological_process |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0003690 | double-stranded DNA binding | IEA | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0010628 | positive regulation of gene expression | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003714 | transcription corepressor activity | TAS | molecular_function |
| GO:0042551 | neuron maturation | IEA | biological_process |