Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PHB2_HUMAN
Description:prohibitin 2 [Source:HGNC Symbol;Acc:30306]
Location:chr12 p13.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S119AQELPsMYQRLBand_7PhosphoSitePlus
S151AKFNAsQLITQBand_7; Med2PhosphoSitePlus
S243LGEALsKNPGYPhosphoSitePlus
T263QNISKtIATSQPhosphoSitePlus
S91RPRKIsSPTGSBand_7PhosphoSitePlus
Y121ELPSMyQRLGLBand_7PhosphoSitePlus
Y34AGAVAyGVRESPhosphoSitePlus
T21PRGMGtALKLLPhosphoSitePlus
Y77IPWFQyPIIYDBand_7PhosphoSitePlus
Y128RLGLDyEERVLBand_7PhosphoSitePlus
S293TRGSDsLIKGKPhosphoSitePlus
S135ERVLPsIVNEVBand_7; Med2PhosphoSitePlus
Y81QYPIIyDIRARBand_7PhosphoSitePlus
Y248SKNPGyIKLRKPhosphoSitePlus; phosphoELM

Dephosphorylation site
PHB2_HUMAN do not have dephosphorylation site.

Mutation site
PHB2_HUMAN do not have mutation site.

Differential expressed protein
PHB2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PHB2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SRPK1_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
CDK4_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
DDR1_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
PKN1_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
KCC1D_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
AURKB_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
KS6B1_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
CDK5_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
WEE1_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
BMR1B_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
PRKY_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
CLK2_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
PHB2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005739mitochondrionIEAcellular_component
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0005743mitochondrial inner membraneIEAcellular_component
GO:0060762regulation of branching involved in mammary gland IEAbiological_process
GO:0033147negative regulation of intracellular estrogen receIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0030331estrogen receptor bindingNASmolecular_function
GO:0005743mitochondrial inner membraneISScellular_component
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0005739mitochondrionIDAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0005634nucleusISScellular_component
GO:0033600negative regulation of mammary gland epithelial ceIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005634nucleusIEAcellular_component
GO:0060749mammary gland alveolus developmentIEAbiological_process
GO:0060744mammary gland branching involved in thelarcheIEAbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23