| UniProt/SwissProt ID: | CCKAR_HUMAN |
| Description: | cholecystokinin A receptor [Source:HGNC Symbol;Acc:1570] |
| Location: | chr4 p15.2 |
| Node attribute: | receptor; PPI(target) |
| Phosphorylation site |
| CCKAR_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| CCKAR_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000295589 | R345S | COSMIC | Lung Cancer | 20668451 | ENSP00000295589 | S180R | COSMIC | Central Nervous System Neoplasms | 21817013 | ENSP00000295589 | S348L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000295589 | S249F | COSMIC | Lung Cancer | 20668451 | ENSP00000295589 | Q238* | COSMIC | Lung Cancer | 20668451 | ENSP00000295589 | Q206H | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| CCKAR_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CCKAR_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CCKN_HUMAN | CCKAR_HUMAN | ligand -> receptor | HPMR |
| IP3KA_HUMAN | CCKAR_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04020 | Calcium signaling pathway |
| hsa04972 | Pancreatic secretion |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007204 | elevation of cytosolic calcium ion concentration | TAS | biological_process |
| GO:0007631 | feeding behavior | TAS | biological_process |
| GO:0004951 | cholecystokinin receptor activity | IEA | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0007586 | digestion | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0007584 | response to nutrient | TAS | biological_process |
| GO:0030900 | forebrain development | IEA | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0007409 | axonogenesis | IEA | biological_process |
| GO:0001764 | neuron migration | IEA | biological_process |
| GO:0007200 | phospholipase C-activating G-protein coupled recep | TAS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |