Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PLCD3_HUMAN
Description:phospholipase C, delta 3 [Source:HGNC Symbol;Acc:9061]
Location:chr17 q21.31
Node attribute:Enzyme(source); Enzyme(target); PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S105IPRAPsQHIFFHPRD; phosphoELM; SysPTM
S496DGRALsDREEEHPRD; phosphoELM; SysPTM
S200DSNQDsKMSFKHPRD

Dephosphorylation site
PLCD3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000313731Q457HCOSMICOvarian Cancer20668451

Differential expressed protein
PLCD3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PLCD3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PI4KA_HUMANPLCD3_HUMANenzyme catalysisKEGG
PI5PA_HUMANPLCD3_HUMANenzyme catalysisKEGG
PLCD3_HUMANIP3KA_HUMANenzyme catalysisKEGG
PLCD3_HUMANFYV1_HUMANenzyme catalysisKEGG
INPP_HUMANPLCD3_HUMANenzyme catalysisKEGG
PLCD3_HUMANPI4KA_HUMANenzyme catalysisKEGG
PLCD3_HUMANIMPA1_HUMANenzyme catalysisKEGG
PLCD3_HUMANPI5PA_HUMANenzyme catalysisKEGG
PLCD3_HUMANPI51C_HUMANenzyme catalysisKEGG
PLCD3_HUMANI5P2_HUMANenzyme catalysisKEGG
PI3R5_HUMANPLCD3_HUMANenzyme catalysisKEGG
PLCD3_HUMANPI3R5_HUMANenzyme catalysisKEGG
PLCD3_HUMANPLCD3_HUMANenzyme catalysisKEGG
PLCD3_HUMANPI42A_HUMANenzyme catalysisKEGG
I5P2_HUMANPLCD3_HUMANenzyme catalysisKEGG
PLCD3_HUMANPTEN_HUMANenzyme catalysisKEGG
PTEN_HUMANPLCD3_HUMANenzyme catalysisKEGG
PI51C_HUMANPLCD3_HUMANenzyme catalysisKEGG
PLCD3_HUMANCDIPT_HUMANenzyme catalysisKEGG
PLCD3_HUMANITPR1_HUMANenzyme catalysisKEGG
DGKA_HUMANPLCD3_HUMANenzyme catalysisKEGG
PLCD3_HUMANDGKA_HUMANenzyme catalysisKEGG
PLCD3_HUMANMTM1_HUMANenzyme catalysisKEGG
PLCD3_HUMANITPR1_HUMANotherKEGG
PLCD3_HUMANKPCA_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa01100Metabolic pathways
hsa04020Calcium signaling pathway
hsa04070Phosphatidylinositol signaling system
hsa00562Inositol phosphate metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006629lipid metabolic processIEAbiological_process
GO:0004871signal transducer activityIEAmolecular_function
GO:0032154cleavage furrowIEAcellular_component
GO:0035556intracellular signal transductionIEAbiological_process
GO:0004435phosphatidylinositol phospholipase C activityIEAmolecular_function
GO:0005509calcium ion bindingIEAmolecular_function
GO:0005543phospholipid bindingIEAmolecular_function
GO:0016042lipid catabolic processIEAbiological_process
GO:0001525angiogenesisIEAbiological_process
GO:0042127regulation of cell proliferationIEAbiological_process
GO:0008081phosphoric diester hydrolase activityIEAmolecular_function
GO:0007165signal transductionIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0005829cytosolIEAcellular_component
GO:0060716labyrinthine layer blood vessel developmentIEAbiological_process


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