Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:UR2R_HUMAN
Description:urotensin 2 receptor [Source:HGNC Symbol;Acc:4468]
Location:chr17 q25.3
Node attribute:receptor; PPI(target)

Phosphorylation site
UR2R_HUMAN do not have phosphorylation site.

Dephosphorylation site
UR2R_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000323516S146RSjoblom2006, COSMIC, HPIBreast Cancer16959974

Differential expressed protein
UR2R_HUMAN is not differential expressed protein.

Hyperphosphorylation site
UR2R_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
UTS2_HUMANUR2R_HUMANligand -> receptorHPMR
IP3KA_HUMANUR2R_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045766positive regulation of angiogenesisIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0055037recycling endosomeIEAcellular_component
GO:0035814negative regulation of renal sodium excretionIEAbiological_process
GO:0045777positive regulation of blood pressureIEAbiological_process
GO:0010841positive regulation of circadian sleep/wake cycle,IEAbiological_process
GO:0048146positive regulation of fibroblast proliferationIEAbiological_process
GO:0005769early endosomeIEAcellular_component
GO:0030307positive regulation of cell growthIEAbiological_process
GO:0045907positive regulation of vasoconstrictionIEAbiological_process
GO:0007165signal transductionTASbiological_process
GO:0016020membraneTAScellular_component
GO:0001604urotensin II receptor activityIEAmolecular_function
GO:0035811negative regulation of urine volumeIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0003105negative regulation of glomerular filtrationIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0045776negative regulation of blood pressureIEAbiological_process
GO:0007204elevation of cytosolic calcium ion concentrationIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0046005positive regulation of circadian sleep/wake cycle,IEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0008015blood circulationTASbiological_process


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