Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NMUR1_HUMAN
Description:neuromedin U receptor 1 [Source:HGNC Symbol;Acc:4518]
Location:chr2 q37.1
Node attribute:receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S171PLQARsMVTRA7tm_1PhosphoSitePlus
Y160LSVERyVAVVH7tm_1; TMPhosphoSitePlus
T174ARSMVtRAHVR7tm_1PhosphoSitePlus

Dephosphorylation site
NMUR1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000305877L11FCOSMICCentral Nervous System Neoplasms18772396
ENSP00000305877W186CCOSMICPancreatic Cancer

Differential expressed protein
NMUR1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NMUR1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NMU_HUMANNMUR1_HUMANligand -> receptorHPMR
NMS_HUMANNMUR1_HUMANligand -> receptorHPMR
IP3KA_HUMANNMUR1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0019722calcium-mediated signalingIDAbiological_process
GO:0008188neuropeptide receptor activityTASmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0007200phospholipase C-activating G-protein coupled recepIDAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0048016inositol phosphate-mediated signalingIDAbiological_process
GO:0008188neuropeptide receptor activityIEAmolecular_function
GO:0007218neuropeptide signaling pathwayTASbiological_process
GO:0007202activation of phospholipase C activityIDAbiological_process
GO:0007218neuropeptide signaling pathwayIEAbiological_process
GO:0006821chloride transportIDAbiological_process
GO:0006816calcium ion transportIDAbiological_process
GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0016021integral to membraneIDAcellular_component
GO:0006939smooth muscle contractionIEPbiological_process
GO:0001607neuromedin U receptor activityIDAmolecular_function
GO:0005886plasma membraneTAScellular_component


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