Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GALR1_HUMAN
Description:galanin receptor 1 [Source:HGNC Symbol;Acc:4132]
Location:chr18 q23
Node attribute:receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y220LICFCyAKVLN7tm_1; TMPhosphoSitePlus
S144HSRRSsSLRVS7tm_1PhosphoSitePlus
S143VHSRRsSSLRV7tm_1PhosphoSitePlus
Y209TFVFGyLLPLL7tm_1; TMPhosphoSitePlus

Dephosphorylation site
GALR1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000299727H263QCOSMICLung Cancer20668451
ENSP00000299727H289RCOSMICOvarian Cancer21720365
ENSP00000299727H327QBIOMARTHepatocellular Carcinoma21930507, 21930502
ENSP00000299727E239QBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
GALR1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GALR1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GCSAM_HUMANGALR1_HUMANligand -> receptorHPMR
GALP_HUMANGALR1_HUMANligand -> receptorHPMR
IP3KA_HUMANGALR1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042923neuropeptide bindingIEAmolecular_function
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0007586digestionTASbiological_process
GO:0007194negative regulation of adenylate cyclase activityTASbiological_process
GO:0007189adenylate cyclase-activating G-protein coupled recIEAbiological_process
GO:0004966galanin receptor activityIEAmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0005886plasma membraneIEAcellular_component
GO:0007218neuropeptide signaling pathwayTASbiological_process
GO:0005886plasma membraneTAScellular_component


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