| UniProt/SwissProt ID: | PI5PA_HUMAN |
| Description: | inositol polyphosphate-5-phosphatase J [Source:HGNC Symbol;Acc:8956] |
| Location: | chr22 q12.2 |
| Node attribute: | Enzyme(target); Enzyme(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S38 | PSKVDsSFQLP | PhosphoSitePlus | |
| S886 | SKRHRsRSPGL | PhosphoSitePlus | |
| S34 | QTGAPsKVDSS | PhosphoSitePlus | |
| S917 | SPSPQsRRLSR | PhosphoSitePlus | |
| S914 | ASRSPsPQSRR | PhosphoSitePlus | |
| T30 | QGVAQtGAPSK | PhosphoSitePlus | |
| Y667 | VGTNKyDTSAK | Exo_endo_phos | PhosphoSitePlus |
| S910 | ERRGAsRSPSP | PhosphoSitePlus | |
| S912 | RGASRsPSPQS | PhosphoSitePlus | |
| S150 | SAGPRsPPVTL | PhosphoSitePlus; phosphoELM | |
| S39 | SKVDSsFQLPA | PhosphoSitePlus | |
| S888 | RHRSRsPGLAR | PhosphoSitePlus | |
| Dephosphorylation site |
| PI5PA_HUMAN do not have dephosphorylation site. |
| Mutation site |
| PI5PA_HUMAN do not have mutation site. |
| Differential expressed protein |
| PI5PA_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PI5PA_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PI5PA_HUMAN | PLCD3_HUMAN | enzyme catalysis | KEGG |
| ITPR1_HUMAN | PI5PA_HUMAN | enzyme catalysis | KEGG |
| INPP_HUMAN | PI5PA_HUMAN | enzyme catalysis | KEGG |
| PLCD3_HUMAN | PI5PA_HUMAN | enzyme catalysis | KEGG |
| PI5PA_HUMAN | IP3KA_HUMAN | enzyme catalysis | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa00562 | Inositol phosphate metabolism |
| hsa01100 | Metabolic pathways |
| hsa04070 | Phosphatidylinositol signaling system |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0033137 | negative regulation of peptidyl-serine phosphoryla | IEA | biological_process |
| GO:0043198 | dendritic shaft | IEA | cellular_component |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0006644 | phospholipid metabolic process | TAS | biological_process |
| GO:0004445 | inositol-polyphosphate 5-phosphatase activity | IEA | molecular_function |
| GO:0010977 | negative regulation of neuron projection developme | IEA | biological_process |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0001726 | ruffle | IEA | cellular_component |
| GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activit | IEA | molecular_function |
| GO:0030426 | growth cone | IEA | cellular_component |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0052659 | inositol-1,3,4,5-tetrakisphosphate 5-phosphatase a | IEA | molecular_function |
| GO:0031115 | negative regulation of microtubule polymerization | IEA | biological_process |
| GO:0034485 | phosphatidylinositol-3,4,5-trisphosphate 5-phospha | IEA | molecular_function |
| GO:0046854 | phosphatidylinositol phosphorylation | IEA | biological_process |
| GO:0006661 | phosphatidylinositol biosynthetic process | TAS | biological_process |