Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:BCL3_HUMAN
Description:B-cell CLL/lymphoma 3 [Source:HGNC Symbol;Acc:998]
Location:chr19 q13.32
Node attribute:substrate; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S402ASPSSsPSQSPPhosphoSitePlus
S41PLRAPsPEPAAHPRD
Y83RPEALyYPGALPhosphoSitePlus
Y84PEALYyPGALLPhosphoSitePlus
S448RPVPPsPAPGGPhosphoSitePlus
S406SSPSQsPPRDPPhosphoSitePlus
S33RPLRAPSPEPAAPRSysPTM 2.0

Dephosphorylation site
BCL3_HUMAN do not have dephosphorylation site.

Mutation site
BCL3_HUMAN do not have mutation site.

Differential expressed protein
BCL3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
BCL3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FAK1_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
M3K7_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
UHMK1_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
NEK2_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
FGR_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
EPHA3_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
KS6A2_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
ACK1_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
CLK2_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
ZAP70_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
FGFR2_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
TRIB3_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
SRPK2_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
MK09_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
GSK3A_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
CDK4_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
NEK9_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
CDK5_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
WEE1_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
KKCC1_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
KC1E_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
GSK3B_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
TYK2_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
TGFR2_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
FAK2_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
MK03_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
TYRO3_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
BUB1_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
MAPK5_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
KSYK_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
PKN1_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
SUH_HUMANBCL3_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
BCL3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0019730antimicrobial humoral responseIEAbiological_process
GO:0032729positive regulation of interferon-gamma productionIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0033257Bcl3/NF-kappaB2 complexIDAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0006351transcription, DNA-dependentIDAbiological_process
GO:0043234protein complexIDAcellular_component
GO:0030330DNA damage response, signal transduction by p53 clIMPbiological_process
GO:0030674protein binding, bridgingTASmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0010225response to UV-CIDAbiological_process
GO:0045064T-helper 2 cell differentiationIEAbiological_process
GO:0042345regulation of NF-kappaB import into nucleusIEPbiological_process
GO:0009615response to virusIDAbiological_process
GO:0042536negative regulation of tumor necrosis factor biosyIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0042742defense response to bacteriumIEAbiological_process
GO:0002268follicular dendritic cell differentiationIEAbiological_process
GO:0051101regulation of DNA bindingIEPbiological_process
GO:0045415negative regulation of interleukin-8 biosynthetic IMPbiological_process
GO:0002467germinal center formationIEAbiological_process
GO:0002455humoral immune response mediated by circulating imIEAbiological_process
GO:0042981regulation of apoptotic processIDAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0002315marginal zone B cell differentiationIEAbiological_process
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0042832defense response to protozoanIEAbiological_process
GO:0048536spleen developmentIEAbiological_process
GO:0008134transcription factor bindingIPImolecular_function
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0006974response to DNA damage stimulusIDAbiological_process
GO:0043066negative regulation of apoptotic processIDAbiological_process
GO:0042088T-helper 1 type immune responseIEAbiological_process
GO:0007249I-kappaB kinase/NF-kappaB cascadeIDAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0045727positive regulation of translationIMPbiological_process
GO:0045082positive regulation of interleukin-10 biosyntheticIEAbiological_process
GO:0000060protein import into nucleus, translocationIMPbiological_process
GO:0030198extracellular matrix organizationIEAbiological_process
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0032996Bcl3-Bcl10 complexIDAcellular_component
GO:0051457maintenance of protein location in nucleusNASbiological_process
GO:0042771intrinsic apoptotic signaling pathway in response IMPbiological_process