Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GNA13_HUMAN
Description:guanine nucleotide binding protein (G protein), alpha 13 [Source:HGNC Symbol;Acc:4381]
Location:chr17 q24.1
Node attribute:PPI(source); substrate; Gprotein; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T203LARRPtKGIHEG-alphaPhosphoSitePlus
T203LARRPtKGIHEPRKACAHPRD
Y44SREKTyVKRLVHPRD
T43LSREKtYVKRLG-alphaPhosphoSitePlus
S9FLPSRsVLSVCG-alphaPhosphoSitePlus
S59LGAGEsGKSTFG-alphaPhosphoSitePlus
S285VFSNVsIILFLG-alphaPhosphoSitePlus
T43LSREKtYVKRLHPRD
S59LGAGEsGKSTFHPRD
T203LARRPtKGIHEPKACaRegPhos
Y44SREKTyVKRLVG-alphaPhosphoSitePlus
T203LARRPtKGIHEPKA_groupphosphoELM; RegPhos

Dephosphorylation site
GNA13_HUMAN do not have dephosphorylation site.

Mutation site
GNA13_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000400717Breast CancerTreatment (mitoxantrone-sensitive vs. mitoxantrone-resistant)cell lineDown0.08516335961

Hyperphosphorylation site
GNA13_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CASR_HUMANGNA13_HUMANGPCR -> GproteingpDB
5HT4R_HUMANGNA13_HUMANGPCR -> GproteingpDB
ADA1A_HUMANGNA13_HUMANGPCR -> GproteingpDB
TA2R_HUMANGNA13_HUMANGPCR -> GproteingpDB
PAR1_HUMANGNA13_HUMANGPCR -> GproteingpDB
DRD5_HUMANGNA13_HUMANGPCR -> GproteingpDB
ACM3_HUMANGNA13_HUMANGPCR -> GproteingpDB
LPAR3_HUMANGNA13_HUMANGPCR -> GproteingpDB
GALR2_HUMANGNA13_HUMANGPCR -> GproteingpDB
LPAR1_HUMANGNA13_HUMANGPCR -> GproteingpDB
S1PR2_HUMANGNA13_HUMANGPCR -> GproteingpDB
S1PR3_HUMANGNA13_HUMANGPCR -> GproteingpDB
C3AR_HUMANGNA13_HUMANGPCR -> GproteingpDB
EDNRA_HUMANGNA13_HUMANGPCR -> GproteingpDB
LPAR2_HUMANGNA13_HUMANGPCR -> GproteingpDB
S1PR5_HUMANGNA13_HUMANGPCR -> GproteingpDB
AGTR1_HUMANGNA13_HUMANGPCR -> GproteingpDB
EDNRB_HUMANGNA13_HUMANGPCR -> GproteingpDB
5HT2C_HUMANGNA13_HUMANGPCR -> GproteingpDB
GNA13_HUMANARHGB_HUMANGprotein -> effectorgpDB
GNA13_HUMANCADH1_HUMANGprotein -> effectorgpDB
GNA13_HUMANKPCD1_HUMANGprotein -> effectorgpDB
GNA13_HUMANARHGC_HUMANGprotein -> effectorgpDB
GNA13_HUMANRASA2_HUMANGprotein -> effectorgpDB
GNA13_HUMANARHG1_HUMANGprotein -> effectorgpDB
KPCA_HUMANGNA13_HUMANkinase -> substrateHPRD
GNA13_HUMANARHGC_HUMANotherKEGG
PAR1_HUMANGNA13_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04810Regulation of actin cytoskeleton
hsa04270Vascular smooth muscle contraction
hsa04730Long-term depression

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005525GTP bindingIEAmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0004871signal transducer activityIEAmolecular_function
GO:0001569patterning of blood vesselsIEAbiological_process
GO:0031702type 1 angiotensin receptor bindingIBAmolecular_function
GO:0007189adenylate cyclase-activating G-protein coupled recIEAbiological_process
GO:0031752D5 dopamine receptor bindingIBAmolecular_function
GO:0031526brush border membraneIBAcellular_component
GO:0005886plasma membraneTAScellular_component
GO:0001701in utero embryonic developmentIEAbiological_process
GO:0006928cellular component movementTASbiological_process
GO:0007243intracellular protein kinase cascadeIEAbiological_process
GO:0019001guanyl nucleotide bindingIEAmolecular_function
GO:0007266Rho protein signal transductionIEAbiological_process
GO:0042470melanosomeIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0007596blood coagulationTASbiological_process
GO:0031584activation of phospholipase D activityIBAbiological_process
GO:0001525angiogenesisIEAbiological_process
GO:0030168platelet activationIEAbiological_process
GO:0006184GTP catabolic processIBAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0031234extrinsic to internal side of plasma membraneIBAcellular_component
GO:0008360regulation of cell shapeIEAbiological_process
GO:0030334regulation of cell migrationIEAbiological_process
GO:0005834heterotrimeric G-protein complexIBAcellular_component
GO:0030154cell differentiationIEAbiological_process
GO:0031683G-protein beta/gamma-subunit complex bindingIBAmolecular_function
GO:0003924GTPase activityIBAmolecular_function
GO:0007165signal transductionTASbiological_process


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