| UniProt/SwissProt ID: | NEK3_HUMAN |
| Description: | NIMA-related kinase 3 [Source:HGNC Symbol;Acc:7746] |
| Location: | chr13 q14.3 |
| Node attribute: | kinase; substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S355 | LRKASsPNLHR | PhosphoSitePlus | |
| T288 | NSKHNtPRKKT | PhosphoSitePlus | |
| S354 | HLRKAsSPNLH | PhosphoSitePlus | |
| S284 | EEIKNsKHNTP | PhosphoSitePlus | |
| S47 | SNTQNsRKEAV | Pkinase | PhosphoSitePlus |
| S462 | DGGHDsVILDP | PhosphoSitePlus | |
| S253 | ATTLLsRGIVA | Pkinase | PhosphoSitePlus |
| S319 | QDRKGsHTDLE | PhosphoSitePlus | |
| Y273 | EIIMEyGEEVL | PhosphoSitePlus | |
| T479 | LDEEDtDFEEE | PhosphoSitePlus | |
| Dephosphorylation site |
| NEK3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| NEK3_HUMAN do not have mutation site. |
| Differential expressed protein |
| NEK3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NEK3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NEK3_HUMAN | ZN213_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | M18BP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | SMAL1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | PSA7L_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | CDA7L_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | ZYX_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | SMRCD_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | MSD2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | HCLS1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | MTA70_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | ZNF81_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | ZN765_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | HSPB1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | KAT5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | 1433Z_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | CRK_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | MRF_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | CENPS_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | LUZP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | CSDC2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | HNRPK_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | ARI3A_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | GCFC1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| MP2K1_HUMAN | NEK3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | PRD10_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | SMPX_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | MTA1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | MDM2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | RNH2C_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | NUP53_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | C2D1A_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | NFAC4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| NEK3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0007049 | cell cycle | NAS | biological_process |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0004674 | protein serine/threonine kinase activity | NAS | molecular_function |
| GO:0006468 | protein phosphorylation | IEA | biological_process |
| GO:0030424 | axon | IEA | cellular_component |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0005634 | nucleus | NAS | cellular_component |
| GO:0007067 | mitosis | NAS | biological_process |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0006468 | protein phosphorylation | ISS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0051301 | cell division | IEA | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0046872 | metal ion binding | IEA | molecular_function |