| UniProt/SwissProt ID: | ZNF81_HUMAN |
| Description: | zinc finger protein 81 [Source:HGNC Symbol;Acc:13156] |
| Location: | chrX p11.23 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y54 | VMLENySHLLS | KRAB | PhosphoSitePlus |
| S106 | SQRRIsGKSTF | PhosphoSitePlus | |
| Y46 | TQRRLyQDVML | KRAB | PhosphoSitePlus |
| S396 | CGKGFsLNSAL | C1_4; IGPD; zf-C2H2; CxxC | PhosphoSitePlus |
| T465 | HQRIHtGEKPY | Zn_Tnp_IS1595 | PhosphoSitePlus |
| T493 | HKRIHtGEKPY | zf-UBP; Rpr2 | PhosphoSitePlus |
| T605 | HQRIHtGEKPY | PhosphoSitePlus | |
| S124 | DTRDDsLYSIL | PhosphoSitePlus | |
| S127 | DDSLYsILEEL | PhosphoSitePlus | |
| T549 | HQTIHtGEKPY | Raffinose_syn; CxxC_CxxC_ | PhosphoSitePlus |
| Dephosphorylation site |
| ZNF81_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000366153 | N264D | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000341151 | N264D | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| ZNF81_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZNF81_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NEK3_HUMAN | ZNF81_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ZNF81_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | sequence-specific DNA binding transcription factor | NAS | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | NAS | biological_process |
| GO:0005634 | nucleus | NAS | cellular_component |
| GO:0008270 | zinc ion binding | IEA | molecular_function |