UniProt/SwissProt ID: | RMP_HUMAN |
Description: | URI1, prefoldin-like chaperone [Source:HGNC Symbol;Acc:13236] |
Location: | chr19 q12 |
Node attribute: | substrate |
Phosphorylation site |
Position | PhosphoPeptide | Catalytic kinase | Source |
---|---|---|---|
S372 | RKRKNsTGSGH | PhosphoSitePlus; HPRD | |
S243 | GEDTTsSEEEK | PhosphoSitePlus; HPRD | |
S488 | EKEFVsPSLTP | PhosphoSitePlus; HPRD | |
S375 | KNSTGsGHSAQ | PhosphoSitePlus | |
S408 | YVPRKsILKSR | PhosphoSitePlus | |
S471 | KLLPLsVTPEA | PhosphoSitePlus | |
T447 | SCEEAtCSDTS | PhosphoSitePlus | |
T373 | KRKNStGSGHS | PhosphoSitePlus | |
S418 | RSRENsVCSDT | PhosphoSitePlus | |
Y403 | VVNGEyVPRKS | PhosphoSitePlus | |
T241 | ANGEDtTSSEE | PhosphoSitePlus; HPRD | |
T354 | NTGKNtTLKFS | PhosphoSitePlus | |
S378 | TGSGHsAQELP | PhosphoSitePlus | |
S440 | RGVLRsISCEE | PhosphoSitePlus | |
T480 | EAFSGtVIEKE | PhosphoSitePlus | |
T492 | VSPSLtPPPAI | HPRD | |
T473 | LPLSVtPEAFS | PhosphoSitePlus | |
T355 | TGKNTtLKFSE | PhosphoSitePlus | |
T242 | NGEDTtSSEEE | PhosphoSitePlus; HPRD | |
S442 | VLRSIsCEEAT | PhosphoSitePlus; HPRD | |
S244 | EDTTSsEEEKE | PhosphoSitePlus; HPRD | |
Dephosphorylation site |
RMP_HUMAN do not have dephosphorylation site. |
Mutation site |
Ensembl ID | Variation | Source | Cancer name | Pubmed |
---|---|---|---|---|
ENSP00000442436 | E364K | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000442436 | R120W | COSMIC | Renal Cancer | 20054297 |
Differential expressed protein |
RMP_HUMAN is not differential expressed protein. |
Hyperphosphorylation site |
RMP_HUMAN do not have hyperphosphorylation site. |
Direct Interaction Pair |
Source | Target | Relationship | Resource |
---|---|---|---|
SCYL2_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
TNI3K_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
CSK21_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
CLK2_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
NEK3_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
PIM2_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
KPCA_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
KC1E_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
ANPRB_HUMAN | RMP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
Function Annotation |
KEGG Pathway |
RMP_HUMAN is not in KEGG pathway. |
Gene Ontology |
GO ID | GO_Term | Evidence | Ontology |
---|---|---|---|
GO:0005634 | nucleus | IDA | cellular_component |
GO:0005739 | mitochondrion | IEA | cellular_component |
GO:0004864 | protein phosphatase inhibitor activity | IEA | molecular_function |
GO:0051082 | unfolded protein binding | IEA | molecular_function |
GO:0003682 | chromatin binding | IDA | molecular_function |
GO:0005737 | cytoplasm | IDA | cellular_component |
GO:0001106 | RNA polymerase II transcription corepressor activi | IDA | molecular_function |
GO:0009615 | response to virus | IMP | biological_process |
GO:0005665 | DNA-directed RNA polymerase II, core complex | IDA | cellular_component |
GO:0071383 | cellular response to steroid hormone stimulus | IDA | biological_process |
GO:0016272 | prefoldin complex | IEA | cellular_component |
GO:0042981 | regulation of apoptotic process | IMP | biological_process |
GO:0006357 | regulation of transcription from RNA polymerase II | IMP | biological_process |
GO:0030425 | dendrite | IEA | cellular_component |
GO:0001558 | regulation of cell growth | IDA | biological_process |
GO:0005515 | protein binding | IPI | molecular_function |
GO:0010923 | negative regulation of phosphatase activity | IMP | biological_process |
GO:0006457 | protein folding | IEA | biological_process |
GO:0000122 | negative regulation of transcription from RNA poly | IDA | biological_process |
GO:0071363 | cellular response to growth factor stimulus | IDA | biological_process |