Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PRD10_HUMAN
Description:PR domain containing 10 [Source:HGNC Symbol;Acc:13995]
Location:chr11 q24.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S424ENGEKsDDGTQPhosphoSitePlus; HPRD
S341KIHDIsEEERKDUF629PhosphoSitePlus
S708KADRIsRSKTFPhosphoSitePlus
S338ENGEKsDDGTQHPRD; phosphoELM
T417IRLEItSENGEHPRD
S418RLEITsENGEKPhosphoSitePlus
S964YVLSEsQSELEHPRD
S1002YVLSEsQSELEHPRD; phosphoELM
S1097YVLSEsQSELEHPRD
S724STDYDsFTFKCPhosphoSitePlus
T331IRLEItSENGEHPRD
T428KSDDGtQDLLHPhosphoSitePlus; HPRD
T342KSDDGtQDLLHHPRD; phosphoELM
S1088YVLSEsQSELEPhosphoSitePlus

Dephosphorylation site
PRD10_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000398431*1062WCOSMICHead and Neck Cancer21798893
ENSP00000302669V247MBIOMARTBreast Cancer21930507, 21930502
ENSP00000432237R722QBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000302669R718QBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000432237V247MBIOMARTBreast Cancer21930507, 21930502
ENSP00000398431R722QBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000398431V247MBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
PRD10_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PRD10_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CLK2_HUMANPRD10_HUMANkinase -> substrateRobert H Newman (2013)
NEK3_HUMANPRD10_HUMANkinase -> substrateRobert H Newman (2013)
TNI3K_HUMANPRD10_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
PRD10_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003677DNA bindingIEAmolecular_function
GO:0008270zinc ion bindingIEAmolecular_function
GO:0005622intracellularIEAcellular_component
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process


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